biostudies-literatureUnknown25Naveed MA<h4>Background</h4>Acute Myocardial Infarction (AMI) in malignancy is a global threat, causing significant mortality and economic burden. They share common risk factors, highlighting the urgency of addressing this critical issue.<h4>Objective</h4>This study analyzed demographic trends and disparities in mortality rates due to AMI in malignancy among adults aged 65 and older from 1999 to 2020.<h4>Methods</h4>We used the CDC WONDER database to analyze Age-adjusted mortality rates (AAMRs) for AMI in malignancy patients (ICD-10 I21, C00-C97) from 1999 to 2020, stratifying by sex, race, geography, and metropolitan status. We calculated Average Annual Percentage Changes (AAPCs) and Annual Percentage Changes (APCs) per 100,000 with 95 % confidence intervals (CI) using Joinpoint regression.<h4>ResInternational journal of cardiology. Cardiovascular risk and prevention200392https://www.ebi.ac.uk/biostudies/studies/S-EPMC11993166biostudies-literatureAcute myocardial infarction-related mortality among older adults (≥65 years) with malignancy in the U.S. from 1999 to 2020.PMC11993166Neppala SPatel BChigurupati HDMubeen MAhmed MFath AUz Zafar MNNaveed MAAzeem BRehan MORana JSAli AIqbal RNaveed HfalseAcute myocardial infarction-related mortality among older adults (≥65 years) with malignancy in the U.S. from 1999 to 2020.<h4>Background</h4>Acute Myocardial Infarction (AMI) in malignancy is a global threat, causing significant mortality and economic burden. They share common risk factors, highlighting the urgency of addressing this critical issue.<h4>Objective</h4>This study analyzed demographic trends and disparities in mortality rates due to AMI in malignancy among adults aged 65 and older from 1999 to 2020.<h4>Methods</h4>We used the CDC WONDER database to analyze Age-adjusted mortality rates (AAMRs) for AMI in malignancy patients (ICD-10 I21, C00-C97) from 1999 to 2020, stratifying by sex, race, geography, and metropolitan status. We calculated Average Annual Percentage Changes (AAPCs) and Annual Percentage Changes (APCs) per 100,000 with 95 % confidence intervals (CI) using Joinpoint regression.<h4>Res2025-01-01T00:00:00Z2025 Jun2025-07-08T03:10:28.456Z2025-07-08T03:10:28.456ZS-EPMC119931664022492410.1016/j.ijcrp.2025.200392