{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["45(9)"],"submitter":["Kataike VM"],"pubmed_abstract":["Oxygen Extraction Fraction (OEF) is a critical measure of a tissue's metabolic state post-ischemic stroke. This study investigated OEF changes in stroke-affected tissue compared to healthy tissue, post-reperfusion. OEF maps generated from gradient echo MRI images of 87 ischemic stroke patients at three time points after successful Endovascular Thrombectomy (EVT) were analysed in a prospective longitudinal multicentre study. Regions of interest (ROIs) delineating the infarct areas and corresponding mirror regions were drawn. The MR-derived OEF index values were obtained from the ROIs and compared using Wilcoxon signed rank tests. The cross-sectional comparison of OEF index values revealed lower values in the infarct areas than the corresponding contralateral areas at all three time points a"],"journal":["Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism"],"pagination":["1748-1759"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11993554"],"repository":["biostudies-literature"],"pubmed_title":["Oxygen extraction fraction changes in ischemic tissue from 24-72 hours to 12 months after successful reperfusion."],"pmcid":["PMC11993554"],"pubmed_authors":["Venkatraman V","Kataike VM","Desmond PM","Mitchell PJ","Campbell BC","Steward C","Ng F"],"additional_accession":[]},"is_claimable":false,"name":"Oxygen extraction fraction changes in ischemic tissue from 24-72 hours to 12 months after successful reperfusion.","description":"Oxygen Extraction Fraction (OEF) is a critical measure of a tissue's metabolic state post-ischemic stroke. This study investigated OEF changes in stroke-affected tissue compared to healthy tissue, post-reperfusion. OEF maps generated from gradient echo MRI images of 87 ischemic stroke patients at three time points after successful Endovascular Thrombectomy (EVT) were analysed in a prospective longitudinal multicentre study. Regions of interest (ROIs) delineating the infarct areas and corresponding mirror regions were drawn. The MR-derived OEF index values were obtained from the ROIs and compared using Wilcoxon signed rank tests. The cross-sectional comparison of OEF index values revealed lower values in the infarct areas than the corresponding contralateral areas at all three time points a","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-29T20:10:25.164Z","creation":"2026-04-08T05:58:27.444Z"},"accession":"S-EPMC11993554","cross_references":{"pubmed":["40219845"],"doi":["10.1177/0271678X251333940"]}}