{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20"],"submitter":["Kiwan P"],"pubmed_abstract":["<h4>Background</h4>The Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen known to cause severe viral hemorrhagic fever.<h4>Aim</h4>We aimed to evaluate the potential circulation of CCHFV in Corsica through a serosurvey, including anonymized residual sera (RS) and high-risk individuals exposed to animals and/or tick bites due to occupational activities.<h4>Methods</h4>This cross-sectional study involved two groups: anonymized RS from medical biology laboratories and sera from high-risk individuals (slaughterhouse workers, veterinary professionals, animal farmers, and rangers) collected across Corsica during 2022-2023. Antibodies targeting the CCHFV viral nucleoprotein were detected using a double-antigen ELISA. ELISA-positive samples underwent neutralizing antibody test"],"journal":["One health (Amsterdam, Netherlands)"],"pagination":["101020"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11995033"],"repository":["biostudies-literature"],"pubmed_title":["Serological evaluation of Crimean-Congo Hemorrhagic fever in humans with High-Risk professional exposure and in residual sera collected in 2022-2023 across Corsica (France)."],"pmcid":["PMC11995033"],"pubmed_authors":["Decarreaux D","Avsic-Zupanc T","Simeoni MH","Canarelli J","Masse S","Gasparine M","Capai L","Falchi A","Charrel R","Kiwan P","Korva M","de Lamballerie X"],"additional_accession":[]},"is_claimable":false,"name":"Serological evaluation of Crimean-Congo Hemorrhagic fever in humans with High-Risk professional exposure and in residual sera collected in 2022-2023 across Corsica (France).","description":"<h4>Background</h4>The Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen known to cause severe viral hemorrhagic fever.<h4>Aim</h4>We aimed to evaluate the potential circulation of CCHFV in Corsica through a serosurvey, including anonymized residual sera (RS) and high-risk individuals exposed to animals and/or tick bites due to occupational activities.<h4>Methods</h4>This cross-sectional study involved two groups: anonymized RS from medical biology laboratories and sera from high-risk individuals (slaughterhouse workers, veterinary professionals, animal farmers, and rangers) collected across Corsica during 2022-2023. Antibodies targeting the CCHFV viral nucleoprotein were detected using a double-antigen ELISA. ELISA-positive samples underwent neutralizing antibody test","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jun","modification":"2025-07-10T03:08:29.416Z","creation":"2025-07-10T03:08:29.416Z"},"accession":"S-EPMC11995033","cross_references":{"pubmed":["40230584"],"doi":["10.1016/j.onehlt.2025.101020"]}}