{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["82"],"submitter":["Lin F"],"pubmed_abstract":["Background
The rate of diagnosis for chronic obstructive pulmonary disease (COPD) is low worldwide. Quantitative computed tomography (QCT) parameters add value to quantify alterations in airway and lung parenchyma for COPD. This study aimed to assess the performance of QCT features in COPD detection using a whole-lung inspiratory CT model.Methods
This multicenter retrospective study was performed on 4106 participants. The derivation cohort containing 1950 participants who enrolled in Guangzhou communities from August 2017 to December 2019, was separated for training and internal validation cohorts, and three external validation cohorts containing 1703 participants were recruited from the public hospitals (Cohort 1: the First Affiliated Hospital of Guangzhou Medical Universi"],"journal":["EClinicalMedicine"],"pagination":["103166"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12002883"],"repository":["biostudies-literature"],"pubmed_title":["AutoCOPD-A novel and practical machine learning model for COPD detection using whole-lung inspiratory quantitative CT measurements: a retrospective, multicenter study."],"pmcid":["PMC12002883"],"pubmed_authors":["Ma Q","Wu L","Shi R","Liang W","Lu W","Liang Z","Ma Y","Wei X","Wang J","Huang R","Liang C","Zheng J","Liu Y","Zhuang J","Zeng Q","He J","Yuan L","Zeng X","Chen H","Xiao T","Xu J","Zhong N","Li Y","Zhang Z","Lin F"],"additional_accession":[]},"is_claimable":false,"name":"AutoCOPD-A novel and practical machine learning model for COPD detection using whole-lung inspiratory quantitative CT measurements: a retrospective, multicenter study.","description":"Background
The rate of diagnosis for chronic obstructive pulmonary disease (COPD) is low worldwide. Quantitative computed tomography (QCT) parameters add value to quantify alterations in airway and lung parenchyma for COPD. This study aimed to assess the performance of QCT features in COPD detection using a whole-lung inspiratory CT model.Methods
This multicenter retrospective study was performed on 4106 participants. The derivation cohort containing 1950 participants who enrolled in Guangzhou communities from August 2017 to December 2019, was separated for training and internal validation cohorts, and three external validation cohorts containing 1703 participants were recruited from the public hospitals (Cohort 1: the First Affiliated Hospital of Guangzhou Medical Universi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-12T03:04:18.549Z","creation":"2025-07-12T03:04:18.549Z"},"accession":"S-EPMC12002883","cross_references":{"pubmed":["40242563"],"doi":["10.1016/j.eclinm.2025.103166"]}}