{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Massey DJ"],"funding":["NIGMS NIH HHS"],"pagination":["iyaf022"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12005266"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["229(4)"],"pubmed_abstract":["Population genetic theory, and the empirical methods built upon it, often assumes that individuals pair randomly for reproduction. However, natural populations frequently violate this assumption, which may potentially confound genome-wide association studies, selection scans, and demographic inference. Within several recently admixed human populations, empirical genetic studies have reported a correlation in global ancestry proportion between spouses, referred to as ancestry-assortative mating. Here, we use forward genomic simulations to link correlations in global ancestry proportion between mates to the underlying mechanistic mate choice process. We consider the impacts of 2 types of mate choice model, using either ancestry-based preferences or social groups as the basis for mate pairing"],"journal":["Genetics"],"pubmed_title":["Differentiating mechanism from outcome for ancestry-assortative mating in admixed human populations."],"pmcid":["PMC12005266"],"funding_grant_id":["R35 GM146926","R35 GM133481"],"pubmed_authors":["Goldberg A","Massey DJ","Szpiech ZA"],"additional_accession":[]},"is_claimable":false,"name":"Differentiating mechanism from outcome for ancestry-assortative mating in admixed human populations.","description":"Population genetic theory, and the empirical methods built upon it, often assumes that individuals pair randomly for reproduction. However, natural populations frequently violate this assumption, which may potentially confound genome-wide association studies, selection scans, and demographic inference. Within several recently admixed human populations, empirical genetic studies have reported a correlation in global ancestry proportion between spouses, referred to as ancestry-assortative mating. Here, we use forward genomic simulations to link correlations in global ancestry proportion between mates to the underlying mechanistic mate choice process. We consider the impacts of 2 types of mate choice model, using either ancestry-based preferences or social groups as the basis for mate pairing","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-06-28T03:05:34.496Z","creation":"2025-06-28T03:05:34.496Z"},"accession":"S-EPMC12005266","cross_references":{"pubmed":["39919029"],"doi":["10.1093/genetics/iyaf022"]}}