biostudies-literatureUnknown39(2)Kim YH<h4>Purpose</h4>To investigate the long-term efficacy and safety of posterior chamber implantable collamer lens (ICL) implantation in high myopia, and the risk factors associated with endothelial cell loss (ECL) or cataract development.<h4>Methods</h4>Medical records of 66 eyes of 37 patients who underwent ICL implantation for high myopia were retrospectively analyzed with a mean follow-up of 12 years. Changes in best-corrected visual acuity (logarithm of the minimum angle of resolution), intraocular pressure (IOP), refractive power, and endothelial cell density over time were analyzed with the incidence of cataract and IOP elevation. Risk factors were analyzed for their association with ECL or cataract development.<h4>Results</h4>At 10 years after surgery, the mean uncorrected visual acuiKorean journal of ophthalmology : KJO134-144https://www.ebi.ac.uk/biostudies/studies/S-EPMC12010185biostudies-literatureLong-term Outcome and Related Risk Factors in Implantable Collamer Lens Implantation of High Myopia.PMC12010185Yoon CHKim YHKim MKfalseLong-term Outcome and Related Risk Factors in Implantable Collamer Lens Implantation of High Myopia.<h4>Purpose</h4>To investigate the long-term efficacy and safety of posterior chamber implantable collamer lens (ICL) implantation in high myopia, and the risk factors associated with endothelial cell loss (ECL) or cataract development.<h4>Methods</h4>Medical records of 66 eyes of 37 patients who underwent ICL implantation for high myopia were retrospectively analyzed with a mean follow-up of 12 years. Changes in best-corrected visual acuity (logarithm of the minimum angle of resolution), intraocular pressure (IOP), refractive power, and endothelial cell density over time were analyzed with the incidence of cataract and IOP elevation. Risk factors were analyzed for their association with ECL or cataract development.<h4>Results</h4>At 10 years after surgery, the mean uncorrected visual acui2025-01-01T00:00:00Z2025 Apr2025-07-07T03:10:03.989Z2025-07-07T03:10:03.989ZS-EPMC120101854000709210.3341/kjo.2024.0094