biostudies-literatureUnknown103Carter MMLallemand Animal NutritionThirty mature Quarter Horse geldings were used in a completely randomized 32-d study to test the hypotheses that supplemental live Saccharomyces cerevisiaeCNCM; I-1077 improves apparent digestion, stabilizes the fecal pH, reduces gut permeability, maintains microbial communities, and decreases inflammation in horses fed a high-starch diet. Horses were stratified by body weight (BW), age, and body condition score (BCS) to one of two treatments: concentrate formulated with 2 g starch · kg BW-1 · meal-1 (control (CON); n = 15) or the same concentrate top-dressed with 25 g/d S. cerevisiae CNCM I-1077 (treatment (SC); n = 15; 8 × 108CFU). Horses were fed individually in stalls every 12 h. Between meals, horses were housed in dry lots with ad libitum access to water and Coastal bermudagrass hay.Journal of animal scienceskaf005https://www.ebi.ac.uk/biostudies/studies/S-EPMC12010697biostudies-literatureInfluence of Saccharomyces cerevisiae CNCM I-1077 on the fecal pH, markers of gut permeability, fecal microbiota, and markers of systemic inflammation in sedentary horses fed a high-starch diet.PMC12010697Paris BLLeatherwood JLGeorge JMGlass KGCarter MMArnold CEMartinez REMoore GERodiles ABradbery ANCox JRKarges KWickersham TAfalseInfluence of Saccharomyces cerevisiae CNCM I-1077 on the fecal pH, markers of gut permeability, fecal microbiota, and markers of systemic inflammation in sedentary horses fed a high-starch diet.Thirty mature Quarter Horse geldings were used in a completely randomized 32-d study to test the hypotheses that supplemental live Saccharomyces cerevisiaeCNCM; I-1077 improves apparent digestion, stabilizes the fecal pH, reduces gut permeability, maintains microbial communities, and decreases inflammation in horses fed a high-starch diet. Horses were stratified by body weight (BW), age, and body condition score (BCS) to one of two treatments: concentrate formulated with 2 g starch · kg BW-1 · meal-1 (control (CON); n = 15) or the same concentrate top-dressed with 25 g/d S. cerevisiae CNCM I-1077 (treatment (SC); n = 15; 8 × 108CFU). Horses were fed individually in stalls every 12 h. Between meals, horses were housed in dry lots with ad libitum access to water and Coastal bermudagrass hay.2025-01-01T00:00:00Z2025 Jan2026-06-06T19:50:54.205Z2026-06-04T03:12:44.894ZS-EPMC120106973980389710.1093/jas/skaf005