{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mundt JM"],"funding":["NCATS NIH HHS","Northwestern University Center for Circadian and Sleep Medicine","NHLBI NIH HHS","NINDS NIH HHS"],"pagination":["e14384"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12012161"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["34(3)"],"pubmed_abstract":["Nightmares are a common symptom in narcolepsy that has not been targeted in prior clinical trials. This study investigated the efficacy of Cognitive Behavioural Therapy for Nightmares (CBT-N), adapted for narcolepsy, in a small group of adults. Given the high prevalence of lucid dreaming in narcolepsy, we added a promising adjuvant component, targeted lucidity reactivation (TLR), a procedure designed to enhance lucid dreaming and dream control. Using a multiple baseline single-case experimental design, adults with narcolepsy and frequent nightmares (≥3/week, N = 6) were randomised to a 2 or 4 week baseline and received seven treatment sessions (CBT-N or CBT-N + TLR). Across the groups, there was a large effect size (between-case standardised mean difference [BC-SMD] = -0.97, 95% CI -1.79 t"],"journal":["Journal of sleep research"],"pubmed_title":["Treating narcolepsy-related nightmares with cognitive behavioural therapy and targeted lucidity reactivation: A pilot study."],"pmcid":["PMC12012161"],"funding_grant_id":["n/a","UL1 TR001422","T32 NS047987","T32 HL007909"],"pubmed_authors":["Byskosh N","Maski K","Casiello-Robbins C","Mundt JM","Konkoly KR","Morris DJ","Mallett R","Pruiksma KE","Torres-Platas SG","Paller KA","Nadorff MR","Franklin RC","Karanth S"],"additional_accession":[]},"is_claimable":false,"name":"Treating narcolepsy-related nightmares with cognitive behavioural therapy and targeted lucidity reactivation: A pilot study.","description":"Nightmares are a common symptom in narcolepsy that has not been targeted in prior clinical trials. This study investigated the efficacy of Cognitive Behavioural Therapy for Nightmares (CBT-N), adapted for narcolepsy, in a small group of adults. Given the high prevalence of lucid dreaming in narcolepsy, we added a promising adjuvant component, targeted lucidity reactivation (TLR), a procedure designed to enhance lucid dreaming and dream control. Using a multiple baseline single-case experimental design, adults with narcolepsy and frequent nightmares (≥3/week, N = 6) were randomised to a 2 or 4 week baseline and received seven treatment sessions (CBT-N or CBT-N + TLR). Across the groups, there was a large effect size (between-case standardised mean difference [BC-SMD] = -0.97, 95% CI -1.79 t","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jun","modification":"2026-06-01T14:49:42.174Z","creation":"2026-04-08T13:33:41.884Z"},"accession":"S-EPMC12012161","cross_references":{"pubmed":["39438131"],"doi":["10.1111/jsr.14384"]}}