biostudies-literatureAschen SZNCATS NIH HHS600-607https://www.ebi.ac.uk/biostudies/studies/S-EPMC12014183biostudies-literatureUnknown281(4)<h4>Objective</h4>To assess rates of surgical complications and postoperative readmission in diabetic patients with and without active perioperative prescriptions for glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications.<h4>Background</h4>With the rapid growth of GLP-1 RA use in the United States, it is important to understand the potential effect of these drugs on surgical outcomes broadly.<h4>Methods</h4>In this retrospective, observational cohort analysis, patients with a diagnosis of type 1 or type 2 diabetes undergoing a surgical procedure at a multicenter quaternary-care health care system between February 2020 and July 2023 were included. Propensity score matching was performed between procedures in patients with and without an active GLP-1 RA prescription. The primary ouAnnals of surgeryAssociation of Perioperative Glucagon-like Peptide-1 Receptor Agonist Use and Postoperative Outcomes.PMC12014183UL1 TR002384Rohde CHSpector JAO'Connell GMAschen SZSalingaros SAndy CZhang AfalseAssociation of Perioperative Glucagon-like Peptide-1 Receptor Agonist Use and Postoperative Outcomes.<h4>Objective</h4>To assess rates of surgical complications and postoperative readmission in diabetic patients with and without active perioperative prescriptions for glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications.<h4>Background</h4>With the rapid growth of GLP-1 RA use in the United States, it is important to understand the potential effect of these drugs on surgical outcomes broadly.<h4>Methods</h4>In this retrospective, observational cohort analysis, patients with a diagnosis of type 1 or type 2 diabetes undergoing a surgical procedure at a multicenter quaternary-care health care system between February 2020 and July 2023 were included. Propensity score matching was performed between procedures in patients with and without an active GLP-1 RA prescription. The primary ou2025-01-01T00:00:00Z2025 Apr2026-06-03T22:50:44.547Z2026-05-02T03:11:45.534ZS-EPMC120141833970406710.1097/SLA.000000000000661410.1097/sla.0000000000006614