{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Cheng X"],"pubmed_abstract":["<h4>Background</h4>Diabetes is one common clinical symptoms of metabolic disorders. The peel of <i>Zea mays</i> L. is a folk remedy for diabetes that has not been thoroughly studied. The effects and mechanisms on diabetes complicated glucose and lipid metabolism disorders are still unknown now.<h4>Purpose</h4>The research is intended to elucidate the constituent of phenylpropanoid enriched of <i>Zea mays</i> L. (YMP), and investigate the treatment and mechanism on amending glucose and lipid metabolism disorders.<h4>Methods</h4>The constituents of YMP were systematacially identified by HPLC-Q-TOF-MS/MS and NMR. To assess the effects of varying YMP doses, diabetic mice induced by streptozotocin and a high-fat diet were divided into groups. Targeted serum metabolomics investigations were cond"],"journal":["Frontiers in pharmacology"],"pagination":["1551713"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12014729"],"repository":["biostudies-literature"],"pubmed_title":["Targeted metabolomics unravels the mechanism by phenylpropanoid-rich of the peel of &lt;i&gt;Zea mays&lt;/i&gt; L. ameliorates metabolic disorders in diabetic mice through gut microbiota modulation."],"pmcid":["PMC12014729"],"pubmed_authors":["Yang Y","Ling B","He Y","Wang A","He J","Chen G","Cheng X"],"additional_accession":[]},"is_claimable":false,"name":"Targeted metabolomics unravels the mechanism by phenylpropanoid-rich of the peel of &lt;i&gt;Zea mays&lt;/i&gt; L. ameliorates metabolic disorders in diabetic mice through gut microbiota modulation.","description":"<h4>Background</h4>Diabetes is one common clinical symptoms of metabolic disorders. The peel of <i>Zea mays</i> L. is a folk remedy for diabetes that has not been thoroughly studied. The effects and mechanisms on diabetes complicated glucose and lipid metabolism disorders are still unknown now.<h4>Purpose</h4>The research is intended to elucidate the constituent of phenylpropanoid enriched of <i>Zea mays</i> L. (YMP), and investigate the treatment and mechanism on amending glucose and lipid metabolism disorders.<h4>Methods</h4>The constituents of YMP were systematacially identified by HPLC-Q-TOF-MS/MS and NMR. To assess the effects of varying YMP doses, diabetic mice induced by streptozotocin and a high-fat diet were divided into groups. Targeted serum metabolomics investigations were cond","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2025-07-02T03:04:51.57Z","creation":"2025-07-02T03:04:51.57Z"},"accession":"S-EPMC12014729","cross_references":{"pubmed":["40271058"],"doi":["10.3389/fphar.2025.1551713"]}}