biostudies-literatureUnknownPassoke S<h4>Background</h4>Data on cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited to studies with small sample sizes. Therefore, we aimed to analyse the extent, characteristics and the longitudinal course of potential cognitive deficits in patients with MOGAD.<h4>Methods</h4>The CogniMOG-Study is a prospective, longitudinal and multicentre observational study of 113 patients with MOGAD. Individual cognitive performance was assessed using the Paced Auditory Serial Addition Task (PASAT), the Symbol Digit Modalities Test (SDMT) and the Multiple Sclerosis Inventory Cognition (MuSIC), which are standardised against normative data from healthy controls. Cognitive performance was assessed at baseline and at 1-year and 2-year follow-up assessJournal of neurology, neurosurgery, and psychiatryjnnp-2024-333994https://www.ebi.ac.uk/biostudies/studies/S-EPMC12015013biostudies-literatureCognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease: a prospective, longitudinal, multicentre study of 113 patients (CogniMOG-Study).PMC12015013Neziraj TKowarik MLeypoldt FOtto CPfeuffer SGraf JHaarmann ARothhammer VFinke CPretzsch RAFrank BNenkov MWandinger KPStoppe MKumpfel TWickel JBellmann-Strobl JGiglhuber KKaste MWeber MSWalter ATauber SKern KSoloroza GTrebst CWeise JGeis CNiehaus SRetzlaff NKern PSteuerwald VWarnke CLadopoulos TNeuhaus OPompsch MHastermann MKorbel KKunzmann VOertel FCSchwab MHoffmann FPakeerathan TZiemann UThen Bergh FHoffmann ODuchow AKramer MLiebetrau MFischer KBerthele AGingele SFreitag FTumani HStern CMarziniak MGahlen ARauer SMelms ADersch RKohler WPache FProtopapa MMaiworm MRostasy KStephanik HAlbrecht PStellmann JPKlotz LFousse MSchwarz PLee DHZettl UGutbrod JSteinbrecher ALuessi FWallwitz UZipp FGehrig JJunghans JSenel MRuprecht KButtmann MKorporal-Kuhnke MSeipelt MBayas AButow FLindenblatt GHaußler VLauenstein ASLandwehr AHummert MWSieb JPNiederschweiberer MSperber PSAngstwurm KLudemann PRehfeldt TLaurent SSchulke RGuthke KLangel SHusseini LParyjas SRingelstein MPaul FKrumbholz MRust RTarampanis AHavla JMeuth SLinker RSommer CBehnke SKretschmer JRPawlitzki MKleinschnitz CHerwerth MStefanou AMering MVKurka NWiendl HIngenhoven KHellwig KHerfurth MAyzenberg IGold RJarius SBittner SPassoke SPul RRuschil CForster MMayer CMetz IRuckriem LEtgen TGass ANeuromyelitis Optica Study Group (NEMOS)Galvao Ribeiro Gomes ABAGroppa SAsseyer SHemmer BWohlrab FYalachkov YAktas OGoereci YKermer PSchwake CKleiter IMeister SRiedlinger AWinkelmann AProebstel AKSturner KTkachenko DLohmann LBednarz NWalz ADawin ESchindler PKopp BSuße MGrothe MPepping SSchraad MNaumann JEngels DPuhlmann HUOy UHRommer PTsaktanis TLehrieder DWildemann BSaggau CfalseCognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease: a prospective, longitudinal, multicentre study of 113 patients (CogniMOG-Study).<h4>Background</h4>Data on cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited to studies with small sample sizes. Therefore, we aimed to analyse the extent, characteristics and the longitudinal course of potential cognitive deficits in patients with MOGAD.<h4>Methods</h4>The CogniMOG-Study is a prospective, longitudinal and multicentre observational study of 113 patients with MOGAD. Individual cognitive performance was assessed using the Paced Auditory Serial Addition Task (PASAT), the Symbol Digit Modalities Test (SDMT) and the Multiple Sclerosis Inventory Cognition (MuSIC), which are standardised against normative data from healthy controls. Cognitive performance was assessed at baseline and at 1-year and 2-year follow-up assess2024-01-01T00:00:00Z2024 Jul2025-07-01T03:05:17.303Z2025-07-01T03:05:17.303ZS-EPMC120150133908486210.1136/jnnp-2024-333994