biostudies-literatureUnknown10(4)Barry KUNDP-UNFPA-UNICEF-WHO-World Bank Special Programme of Research, Development and Research Training in Human Reproductionthe United States GovernmentFederal Ministry of HealthGovernment of CanadaNational Institute for Health and Care ResearchBirmingham Biomedical Research Centre<h4>Background</h4>Pregnant and recently pregnant women infected with SARS-CoV-2 are at increased risk of death and serious complications than those without the infection. The extent of variation in mortality rates in pregnant women with SARS-CoV-2 infection across regions, and the causes of death are not known. We systematically reviewed all available evidence on the variation in mortality rates in pregnant women with SARS-CoV-2 infection across geographical and country income groups, and the reported cause of death.<h4>Methods</h4>We searched major databases (December 2019-January 2023) including Medline, LILACS, BIREME and Embase. We included studies that reported deaths in at least 10 consecutive pregnant or recently pregnant women with confirmed SARS-CoV-2 infection and assessed the sBMJ global healthe015815https://www.ebi.ac.uk/biostudies/studies/S-EPMC12015698biostudies-literatureGlobal maternal mortality associated with SARS-CoV-2 infection: a systematic review and meta-analysis.PMC12015698Shepherd-Evans IKhashaba AKhalil AKing YFernandez-Garcia SHebbar Mvan Wely MKara EMahmoud GThorson AAttarde SFraser HGupta ALawson Hvan Leeuwen EZhou DKumaran MKhalil HKostova EThangaratinam SAnsari KRajah TDixit AO'Donoghue KMofenson LWalker KKew TRoncal Redin MYap MOladapo OTLittmoden MBanjoko AMamey MKunst HKim CRZamora JAkande DBarry KAllotey JPregCOV-19 Living Systematic Review ConsortiumBrizuela VRuiz-Calvo GSheikh JBonet MfalseGlobal maternal mortality associated with SARS-CoV-2 infection: a systematic review and meta-analysis.<h4>Background</h4>Pregnant and recently pregnant women infected with SARS-CoV-2 are at increased risk of death and serious complications than those without the infection. The extent of variation in mortality rates in pregnant women with SARS-CoV-2 infection across regions, and the causes of death are not known. We systematically reviewed all available evidence on the variation in mortality rates in pregnant women with SARS-CoV-2 infection across geographical and country income groups, and the reported cause of death.<h4>Methods</h4>We searched major databases (December 2019-January 2023) including Medline, LILACS, BIREME and Embase. We included studies that reported deaths in at least 10 consecutive pregnant or recently pregnant women with confirmed SARS-CoV-2 infection and assessed the s2025-01-01T00:00:00Z2025 Apr2025-07-07T03:10:09.04Z2025-07-07T03:10:09.04ZS-EPMC120156984025863410.1136/bmjgh-2024-015815