{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2023"],"submitter":["Lei J"],"pubmed_abstract":["Porcine epidemic diarrhea virus (PEDV) is a porcine enteric coronavirus globally, causing serious economic losses to the global pig industry since 2010. Here, a PEDV CH/Yinchuan/2021 strain was isolated in a CV777-vaccinated sow farm which experienced a large-scale PEDV invasion in Yinchuan, China, in 2021. Our results demonstrated that the CH/Yinchuan/2021 isolate could efficiently propagate in Vero cells, and its proliferation ability was weaker than that of CV777 at 10 passages (P10). Phylogenetic analysis of the S gene revealed that CH/Yinchuan/2021 was clustered into subgroup GIIa, forming an independent branch with 2020-2021 isolates in China. Moreover, GII was obviously allocated into four clades, showing regional and temporal differences in PEDV global isolates. Notably, CH/Yinchua"],"journal":["Transboundary and emerging diseases"],"pagination":["7082352"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12016728"],"repository":["biostudies-literature"],"pubmed_title":["A Porcine Epidemic Diarrhea Virus Isolated from a Sow Farm Vaccinated with CV777 Strain in Yinchuan, China: Characterization, Antigenicity, and Pathogenicity."],"pmcid":["PMC12016728"],"pubmed_authors":["Liu H","Lei J","Han Y","Chen H","Chang Z","Zhang S","Fang Y","Lu K","Yang Z","Guan Z","Lu H","Xiang C","Miao Y","Wang X","Hu R"],"additional_accession":[]},"is_claimable":false,"name":"A Porcine Epidemic Diarrhea Virus Isolated from a Sow Farm Vaccinated with CV777 Strain in Yinchuan, China: Characterization, Antigenicity, and Pathogenicity.","description":"Porcine epidemic diarrhea virus (PEDV) is a porcine enteric coronavirus globally, causing serious economic losses to the global pig industry since 2010. Here, a PEDV CH/Yinchuan/2021 strain was isolated in a CV777-vaccinated sow farm which experienced a large-scale PEDV invasion in Yinchuan, China, in 2021. Our results demonstrated that the CH/Yinchuan/2021 isolate could efficiently propagate in Vero cells, and its proliferation ability was weaker than that of CV777 at 10 passages (P10). Phylogenetic analysis of the S gene revealed that CH/Yinchuan/2021 was clustered into subgroup GIIa, forming an independent branch with 2020-2021 isolates in China. Moreover, GII was obviously allocated into four clades, showing regional and temporal differences in PEDV global isolates. Notably, CH/Yinchua","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023","modification":"2026-04-08T18:46:15.621Z","creation":"2025-07-08T03:10:48.781Z"},"accession":"S-EPMC12016728","cross_references":{"pubmed":["40303733"],"doi":["10.1155/2023/7082352"]}}