biostudies-literatureRen ZGuangdong Provincial Forestry Department’s Provincial Financial Special Fund for Ecological Forestry Construction-Wildlife ConservationScientific and Technological Planning Project of Guangzhou CityProject of Collaborative Innovation Center of GDAASSpecial Fund for Scientific Innovation Strategy-Construction of High-level Academy of Agriculture ScienceGuangdong Modern Agroindustry Technology Research SystemYunnan Liao Ming Expert WorkstationAgricultural Science and Technology Innovation for the 14th Five-Year Plan of Guangdong ProvinceGuangdong Science and Technology Department6668569https://www.ebi.ac.uk/biostudies/studies/S-EPMC12017068biostudies-literatureUnknown2023Circoviruses are a group of small circular, single-stranded DNA viruses that belong to the family <i>Circoviridae</i>. They are known to infect a wide variety of animals. <i>Rhizomys sinensis</i> is a species of rodent that is the reservoir of many zoonotic pathogens. Our previous study identified many sequencing reads mapped to the genome of viruses in <i>Circoviridae</i> in <i>R. sinensis</i>. However, little is known about the circulation and genetic characterization of circoviruses in <i>R. sinensis</i>. This study identified three different circoviruses in samples from 195 <i>R. sinensis</i>. First, the bamboo rat circovirus is widely prevalent in <i>R. sinensis</i> in Guangdong Province, and all strains could be divided into three clades based on nucleotide substitutions at specific Transboundary and emerging diseasesThe Genetic Diversity and Interspecific Transmission of Circovirus in <i>Rhizomys sinensis</i> in Guangdong, Southern China.PMC12017068202105AF1500772023E04J12562022KJ1142022SDZG02XTXM2022022021B1212050021R2020PY-JC001Hua YCai RChen JRen ZSun CWang GXiang HYu JYuan HZhang PLi NHuang YChen XWang XLuo SLiao MYuan ZGfalseThe Genetic Diversity and Interspecific Transmission of Circovirus in <i>Rhizomys sinensis</i> in Guangdong, Southern China.Circoviruses are a group of small circular, single-stranded DNA viruses that belong to the family <i>Circoviridae</i>. They are known to infect a wide variety of animals. <i>Rhizomys sinensis</i> is a species of rodent that is the reservoir of many zoonotic pathogens. Our previous study identified many sequencing reads mapped to the genome of viruses in <i>Circoviridae</i> in <i>R. sinensis</i>. However, little is known about the circulation and genetic characterization of circoviruses in <i>R. sinensis</i>. This study identified three different circoviruses in samples from 195 <i>R. sinensis</i>. First, the bamboo rat circovirus is widely prevalent in <i>R. sinensis</i> in Guangdong Province, and all strains could be divided into three clades based on nucleotide substitutions at specific 2023-01-01T00:00:00Z20232026-06-01T10:17:20.956Z2025-07-10T03:09:09.976ZS-EPMC120170684030377110.1155/2023/6668569