{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bell RA"],"funding":["National Center for Advancing Translational Sciences","NCATS NIH HHS","NCCDPHP CDC HHS","Medical University of South Carolina","National Institute of Diabetes and Digestive and Kidney Diseases","NHLBI NIH HHS","University of Cincinnati","HSRD VA","Seattle Children&apos;s Hospital","Centers for Disease Control and Prevention","Ohio Department of Health","NIDDK NIH HHS","EPA","University of Colorado Denver","University of North Carolina at Chapel Hill"],"pagination":["5213520"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12017249"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2024"],"pubmed_abstract":["<h4>Objectives</h4>Cardiovascular disease (CVD) is the leading cause of death and disability among persons with diabetes. Early intervention on cardiovascular risk factors (CRFs) is important in reducing CVD burden. The SEARCH for Diabetes in Youth study assessed CRFs in incident cohorts of youth aged <20 years established from 2002 to 2016. <i>Research Design and Methods</i>. Regression models assessed trends over each incident year for lipids (total cholesterol (TC), HDL-c, LDL-c, triglycerides (TG), VLDL-c, and non-HDL-c), kidney function (albumin/creatinine ratio (ACR) ≥30 and ≥300, cystatin C, serum creatinine and estimated glomerular filtration rate (eGFR)), systolic and diastolic blood pressure (BP) <i>z</i>-scores, BMI <i>z</i>-score, waist circumference (WC), and an inflammatory m"],"journal":["Pediatric diabetes"],"pubmed_title":["Trends in CVD Risk Factors for Youth with Incident Diabetes: SEARCH for Diabetes in Youth."],"pmcid":["PMC12017249"],"funding_grant_id":["U18 DP006131","U18 DP006133","U01 DP000248","U01 DP000247","U01 DP000246","U18 DP006134","UL1 TR000077","UL1 TR000154","U01 DP000244","U18 DP006136","U18DP002708","UL1 TR001425","DP-15-002","1U18DP006131","U18 DP002710","EP-C-15-002","U18 DP006139","R01 DK127208","U18 DP006138","R01 HL146818","UC4 DK108173","U48/CCU819241-3","U18 DP002714","DP-05-069","UL1 TR001450","UL1 TR000062","U01 DP000254","UL1 TR000423","U01 DP000250","U18DP002710-01","00097","P30 DK057516","U18DP006139","U48/CCU419249","U18DP006138","HIR 10-001","U18 DP002709","K23 HL148394","U18DP006136","1R01DK127208-01","U18 DP002708","U18DP006134","U18DP006133","DP-10-001","1UC4DK108173","U18DP000247-06A1","U58/CCU019235-4"],"pubmed_authors":["Bellatorre A","Divers J","Marcovina SM","Pettitt DJ","D'Agostino R","Dolan LM","Jensen E","Liese AD","Dabelea D","South AM","Wagenknecht LE","Bell RA","Shah AS","Lustigova E","Merjaneh L","Pihoker C","Rigdon J"],"additional_accession":[]},"is_claimable":false,"name":"Trends in CVD Risk Factors for Youth with Incident Diabetes: SEARCH for Diabetes in Youth.","description":"<h4>Objectives</h4>Cardiovascular disease (CVD) is the leading cause of death and disability among persons with diabetes. Early intervention on cardiovascular risk factors (CRFs) is important in reducing CVD burden. The SEARCH for Diabetes in Youth study assessed CRFs in incident cohorts of youth aged <20 years established from 2002 to 2016. <i>Research Design and Methods</i>. Regression models assessed trends over each incident year for lipids (total cholesterol (TC), HDL-c, LDL-c, triglycerides (TG), VLDL-c, and non-HDL-c), kidney function (albumin/creatinine ratio (ACR) ≥30 and ≥300, cystatin C, serum creatinine and estimated glomerular filtration rate (eGFR)), systolic and diastolic blood pressure (BP) <i>z</i>-scores, BMI <i>z</i>-score, waist circumference (WC), and an inflammatory m","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-06-06T16:49:16.808Z","creation":"2025-07-04T03:05:45.611Z"},"accession":"S-EPMC12017249","cross_references":{"pubmed":["40302976"],"doi":["10.1155/2024/5213520"]}}