{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Zhou W"],"pubmed_abstract":["<h4>Background</h4>The association between serum potassium and prodromal Parkinson's disease (PPD) remains unclear currently.<h4>Objective</h4>The ultimate goal is to gain a deeper understanding of the implications of this association between serum potassium and PPD.<h4>Methods</h4>We conducted a retrospective cross-sectional study involving 1035 participants in PPMI cohort. Age, sex, education years, race, body mass index (BMI), calcium, alanine aminotransferase, aspartate aminotransferase, lymphocytes, neutrophils, serum uric acid, serum sodium, serum potassium, creatinine, serum glucose were obtained from all participants. Logistic regression, and smooth curve fitting were utilized to substantiate the research objectives.<h4>Results</h4>The overall PPD was 83.4 % (863/1035). Multivariat"],"journal":["Clinical parkinsonism & related disorders"],"pagination":["100323"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12017917"],"repository":["biostudies-literature"],"pubmed_title":["Identification of inverted U-shaped curve association between serum potassium and prodromal Parkinson's disease."],"pmcid":["PMC12017917"],"pubmed_authors":["Xia Q","Zhou W","Gong L","Liu D","Li JY"],"additional_accession":[]},"is_claimable":false,"name":"Identification of inverted U-shaped curve association between serum potassium and prodromal Parkinson's disease.","description":"<h4>Background</h4>The association between serum potassium and prodromal Parkinson's disease (PPD) remains unclear currently.<h4>Objective</h4>The ultimate goal is to gain a deeper understanding of the implications of this association between serum potassium and PPD.<h4>Methods</h4>We conducted a retrospective cross-sectional study involving 1035 participants in PPMI cohort. Age, sex, education years, race, body mass index (BMI), calcium, alanine aminotransferase, aspartate aminotransferase, lymphocytes, neutrophils, serum uric acid, serum sodium, serum potassium, creatinine, serum glucose were obtained from all participants. Logistic regression, and smooth curve fitting were utilized to substantiate the research objectives.<h4>Results</h4>The overall PPD was 83.4 % (863/1035). Multivariat","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2025-07-10T03:09:02.128Z","creation":"2025-07-10T03:09:02.128Z"},"accession":"S-EPMC12017917","cross_references":{"pubmed":["40271390"],"doi":["10.1016/j.prdoa.2025.100323"]}}