{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Han F"],"pubmed_abstract":["<h4>Background</h4>The precise function of the hs-CRP/HDL-C ratio in forecasting the long-term mortality risk of patients with stages 1-4 of Cardiovascular-Kidney-Metabolic (CKM) syndrome remains inadequately delineated. This study investigates the potential correlation between the hs-CRP/HDL-C ratio and long-term mortality risk in individuals with CKM syndrome stages 1-4.<h4>Methods</h4>This prospective cohort study utilises data from the China Health and Retirement Longitudinal Study (CHARLS) project, encompassing 6,719 people who satisfied stringent criteria. We developed three Cox proportional hazards regression models to investigate the potential relationship between the hs-CRP/HDL-C ratio and long-term mortality risk in patients with CKM stages 1-4. We employed Restricted Cubic Splin"],"journal":["Frontiers in endocrinology"],"pagination":["1552219"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12018248"],"repository":["biostudies-literature"],"pubmed_title":["hs-CRP/HDL-C can predict the risk of all cause mortality in cardiovascular-kidney-metabolic syndrome stage 1-4 patients."],"pmcid":["PMC12018248"],"pubmed_authors":["Zheng Y","Guo H","Zhang H","Han F"],"additional_accession":[]},"is_claimable":false,"name":"hs-CRP/HDL-C can predict the risk of all cause mortality in cardiovascular-kidney-metabolic syndrome stage 1-4 patients.","description":"<h4>Background</h4>The precise function of the hs-CRP/HDL-C ratio in forecasting the long-term mortality risk of patients with stages 1-4 of Cardiovascular-Kidney-Metabolic (CKM) syndrome remains inadequately delineated. This study investigates the potential correlation between the hs-CRP/HDL-C ratio and long-term mortality risk in individuals with CKM syndrome stages 1-4.<h4>Methods</h4>This prospective cohort study utilises data from the China Health and Retirement Longitudinal Study (CHARLS) project, encompassing 6,719 people who satisfied stringent criteria. We developed three Cox proportional hazards regression models to investigate the potential relationship between the hs-CRP/HDL-C ratio and long-term mortality risk in patients with CKM stages 1-4. We employed Restricted Cubic Splin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2025-07-06T03:04:14.118Z","creation":"2025-07-06T03:04:14.118Z"},"accession":"S-EPMC12018248","cross_references":{"pubmed":["40276550"],"doi":["10.3389/fendo.2025.1552219"]}}