biostudies-literatureUnknown15Sthity RA<h4>Introduction</h4>Environmental enteric dysfunction (EED), a subclinical intestinal disorder, is characterized by chronic fecal-oral exposure to entero-pathogens and could be diagnosed by measuring non-invasive biomarkers. <i>Escherichia coli</i> is the one of the key bacterial enteric pathogens that drives EED, but there is a lack of information on the <i>E. coli</i> pathotypes in relation to the biomarkers of EED in malnourished adults. Here, we intended to measure the possible association of these pathotypes with EED biomarkers and nutritional status of adults residing in a slum in Bangladesh.<h4>Method</h4>Fecal samples were collected from 524 malnourished adults (BMI ≤18.5 kg/m²) living in a slum-setting in Dhaka from March 2016 to September 2019 and analyzed by TaqMan AFrontiers in cellular and infection microbiology1553688https://www.ebi.ac.uk/biostudies/studies/S-EPMC12018316biostudies-literatureAssociation of &lt;i&gt;Escherichia coli&lt;/i&gt; pathotypes with fecal markers of enteropathy and nutritional status among underweight adults in Bangladesh.PMC12018316Kabir MMAhmed TMahfuz MIslam MZGazi MASagar MEKFerdous JSthity RAMostafa IfalseAssociation of &lt;i&gt;Escherichia coli&lt;/i&gt; pathotypes with fecal markers of enteropathy and nutritional status among underweight adults in Bangladesh.<h4>Introduction</h4>Environmental enteric dysfunction (EED), a subclinical intestinal disorder, is characterized by chronic fecal-oral exposure to entero-pathogens and could be diagnosed by measuring non-invasive biomarkers. <i>Escherichia coli</i> is the one of the key bacterial enteric pathogens that drives EED, but there is a lack of information on the <i>E. coli</i> pathotypes in relation to the biomarkers of EED in malnourished adults. Here, we intended to measure the possible association of these pathotypes with EED biomarkers and nutritional status of adults residing in a slum in Bangladesh.<h4>Method</h4>Fecal samples were collected from 524 malnourished adults (BMI ≤18.5 kg/m²) living in a slum-setting in Dhaka from March 2016 to September 2019 and analyzed by TaqMan A2025-01-01T00:00:00Z20252025-06-26T03:06:06.219Z2025-06-26T03:06:06.219ZS-EPMC120183164027638610.3389/fcimb.2025.1553688