{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jain S"],"funding":["NIA NIH HHS","NHLBI NIH HHS"],"pagination":["1816-1827"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12019769"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["52(12)"],"pubmed_abstract":["<h4>Objectives</h4>Older adults who survive critical illness are at risk for increased disability, limiting their independence and quality of life. We sought to evaluate whether the occurrence of symptoms that restrict activity, that is, restricting symptoms, is associated with increased disability following an ICU hospitalization.<h4>Design</h4>Prospective longitudinal study of community-living adults 70 years old or older who were interviewed monthly between 1998 and 2018.<h4>Setting</h4>South Central Connecticut, United States.<h4>Patients</h4>Two hundred fifty-one ICU admissions from 202 participants who were discharged alive from the hospital.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>Occurrence of 15 restricting symptoms (operationalized as number of symptoms an"],"journal":["Critical care medicine"],"pubmed_title":["Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults."],"pmcid":["PMC12019769"],"funding_grant_id":["K76 AG057023","P30 AG021342","K12 HL138037","R01 AG017560","R03 AG078942"],"pubmed_authors":["Jain S","Han L","Feder SL","Ferrante LE","Leo-Summers L","Gill TM","Gahbauer EA"],"additional_accession":[]},"is_claimable":false,"name":"Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults.","description":"<h4>Objectives</h4>Older adults who survive critical illness are at risk for increased disability, limiting their independence and quality of life. We sought to evaluate whether the occurrence of symptoms that restrict activity, that is, restricting symptoms, is associated with increased disability following an ICU hospitalization.<h4>Design</h4>Prospective longitudinal study of community-living adults 70 years old or older who were interviewed monthly between 1998 and 2018.<h4>Setting</h4>South Central Connecticut, United States.<h4>Patients</h4>Two hundred fifty-one ICU admissions from 202 participants who were discharged alive from the hospital.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>Occurrence of 15 restricting symptoms (operationalized as number of symptoms an","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2025-07-10T03:08:57.11Z","creation":"2025-07-10T03:08:57.11Z"},"accession":"S-EPMC12019769","cross_references":{"pubmed":["39298623"],"doi":["10.1097/ccm.0000000000006427","10.1097/CCM.0000000000006427"]}}