{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bruera S"],"funding":["Duncan Family Institute for Cancer Prevention and Risk Assessment","Susan G. Komen Breast Cancer Foundation","National Cancer Institute","NCI NIH HHS","Cancer Prevention and Research Institute of Texas"],"pagination":["559-568"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12019812"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["75(3)"],"pubmed_abstract":["<h4>Objective</h4>Patients with cancer and systemic lupus erythematosus (SLE) may have worse outcomes than those without SLE, given their comorbidities. We examined survival in elderly women with breast cancer (BC) and SLE and hypothesized that survival would be decreased compared with women with BC but without SLE.<h4>Methods</h4>We identified patients with BC and SLE and patients with BC without SLE in the Texas Cancer Registry and Surveillance, Epidemiology, and End Results, linked to Medicare claims. Overall survival (OS) was estimated after matching (age and cancer stage) and in multivariable Cox proportional hazards models adjusting for other cancer characteristics, treatment, and comorbidities. Two additional cohorts of women without cancer with and without SLE were also studied.<h4"],"journal":["Arthritis care & research"],"pubmed_title":["Systemic Lupus Erythematosus and Mortality in Elderly Patients With Early Breast Cancer."],"pmcid":["PMC12019812"],"funding_grant_id":["SAC‐150061","P30 CA016672","RP‐160674","P‐30‐CA‐016672"],"pubmed_authors":["Vinod S","Lei X","Giordano SH","Pundole X","Suarez-Almazor ME","Bruera S","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"Systemic Lupus Erythematosus and Mortality in Elderly Patients With Early Breast Cancer.","description":"<h4>Objective</h4>Patients with cancer and systemic lupus erythematosus (SLE) may have worse outcomes than those without SLE, given their comorbidities. We examined survival in elderly women with breast cancer (BC) and SLE and hypothesized that survival would be decreased compared with women with BC but without SLE.<h4>Methods</h4>We identified patients with BC and SLE and patients with BC without SLE in the Texas Cancer Registry and Surveillance, Epidemiology, and End Results, linked to Medicare claims. Overall survival (OS) was estimated after matching (age and cancer stage) and in multivariable Cox proportional hazards models adjusting for other cancer characteristics, treatment, and comorbidities. Two additional cohorts of women without cancer with and without SLE were also studied.<h4","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Mar","modification":"2025-07-06T03:04:16.555Z","creation":"2025-07-06T03:04:16.555Z"},"accession":"S-EPMC12019812","cross_references":{"pubmed":["34558796"],"doi":["10.1002/acr.24793"]}}