{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shingyouchi Y"],"funding":["Japan Society for the Promotion of Science London","Takahashi Industrial and Economic Research Foundation","Yazaki Memorial Foundation for Science and Technology","Scientific Research on Innovative Areas \"Aquatic Functional Materials\"","Kumagai Foundation for Science and Technology","Scientific Research on Innovative Areas","Iwatani Naoji Foundation","Joint Usage/Research Center for Catalysis","Japan Society for the Promotion of Science"],"pagination":["e2409910"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12019909"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(16)"],"pubmed_abstract":["The electrochemical CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR) has been extensively studied because it can be leveraged to directly convert CO<sub>2</sub> into valuable hydrocarbons. Among the various catalysts, copper nanoclusters (Cu NCs) exhibit high selectivity and efficiency for producing CO<sub>2</sub>RR products owing to their unique geometric/electronic structures. However, the influence of protective ligands on the CO<sub>2</sub>RR performance of Cu NCs remains unclear. In this study, it is shown that different thiolate ligands, despite having nearly identical geometries, can substantially affect the electrochemical stability of Cu<sub>14</sub> NCs in the CO<sub>2</sub>RR. Notably, Cu<sub>14</sub> NCs protected by 2-phenylethanethiolate exhibit greater stability and achieve a relatively higher selectivity (≈40%) for formic acid production compared with the cyclohexanethiolate-protected counterpart. These insights are crucial for designing Cu NCs that are both stable and highly selective, enhancing their efficacy for electrochemical CO<sub>2</sub> reduction."],"journal":["Small (Weinheim an der Bergstrasse, Germany)"],"pubmed_title":["Ligand-Dependent Intracluster Interactions in Electrochemical CO&lt;sub&gt;2&lt;/sub&gt; Reduction Using Cu&lt;sub&gt;14&lt;/sub&gt; Nanoclusters."],"pmcid":["PMC12019909"],"funding_grant_id":["22AY0056","22K19012","22H04562","24K01459","23AY0189","23H00289"],"pubmed_authors":["Ikeda K","Negishi Y","Hossain S","Metha GF","Biswas S","Osborn DJ","Tanaka T","Yoshigoe Y","Kawawaki T","Ogami M","Shingyouchi Y","Kamiyama M"],"additional_accession":[]},"is_claimable":false,"name":"Ligand-Dependent Intracluster Interactions in Electrochemical CO&lt;sub&gt;2&lt;/sub&gt; Reduction Using Cu&lt;sub&gt;14&lt;/sub&gt; Nanoclusters.","description":"The electrochemical CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR) has been extensively studied because it can be leveraged to directly convert CO<sub>2</sub> into valuable hydrocarbons. Among the various catalysts, copper nanoclusters (Cu NCs) exhibit high selectivity and efficiency for producing CO<sub>2</sub>RR products owing to their unique geometric/electronic structures. However, the influence of protective ligands on the CO<sub>2</sub>RR performance of Cu NCs remains unclear. In this study, it is shown that different thiolate ligands, despite having nearly identical geometries, can substantially affect the electrochemical stability of Cu<sub>14</sub> NCs in the CO<sub>2</sub>RR. Notably, Cu<sub>14</sub> NCs protected by 2-phenylethanethiolate exhibit greater stability and achieve a relatively higher selectivity (≈40%) for formic acid production compared with the cyclohexanethiolate-protected counterpart. These insights are crucial for designing Cu NCs that are both stable and highly selective, enhancing their efficacy for electrochemical CO<sub>2</sub> reduction.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-06-26T03:05:31.038Z","creation":"2025-06-26T03:05:31.038Z"},"accession":"S-EPMC12019909","cross_references":{"pubmed":["39632376"],"doi":["10.1002/smll.202409910"]}}