{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["103"],"submitter":["Singh P"],"pubmed_abstract":["This study investigated the effects of up to 45% inclusion of whole pulse ingredients in grain-free (GF) diets on the excretion of bile acids (BAs) and other fecal metabolites in healthy large-breed dogs. Twenty-eight adult Siberian Huskies were fed 1 of 4 experimental diets formulated to meet the same macronutrient profiles for 20 wk: 1) grain-inclusive diet with 45% corn (Ctl), 2) GF diet with 15% pulses (Pulse15), 3) GF diet with 30% pulses (Pulse30), 4) GF diet with 45% pulses (Pulse45). All diets included chicken meal and pea starch. Fecal samples were collected on weeks 2 and 19. Bile acids were analyzed using ultra-performance liquid chromatography-MRM/MS technology, while fecal metabolites were analyzed using Agilent HP1000 high-performance liquid chromatography. Bile acids and fec"],"journal":["Journal of animal science"],"pagination":["skaf075"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12019969"],"repository":["biostudies-literature"],"pubmed_title":["Whole pulse ingredient inclusion in macronutrient-balanced diets increased fecal concentrations of propionic acid but not total bile acids in healthy adult large-breed dogs after 20 weeks."],"pmcid":["PMC12019969"],"pubmed_authors":["Singh P","Saunders-Blades J","Swanson KS","Squires EJ","Oba PM","Shoveller AK"],"additional_accession":[]},"is_claimable":false,"name":"Whole pulse ingredient inclusion in macronutrient-balanced diets increased fecal concentrations of propionic acid but not total bile acids in healthy adult large-breed dogs after 20 weeks.","description":"This study investigated the effects of up to 45% inclusion of whole pulse ingredients in grain-free (GF) diets on the excretion of bile acids (BAs) and other fecal metabolites in healthy large-breed dogs. Twenty-eight adult Siberian Huskies were fed 1 of 4 experimental diets formulated to meet the same macronutrient profiles for 20 wk: 1) grain-inclusive diet with 45% corn (Ctl), 2) GF diet with 15% pulses (Pulse15), 3) GF diet with 30% pulses (Pulse30), 4) GF diet with 45% pulses (Pulse45). All diets included chicken meal and pea starch. Fecal samples were collected on weeks 2 and 19. Bile acids were analyzed using ultra-performance liquid chromatography-MRM/MS technology, while fecal metabolites were analyzed using Agilent HP1000 high-performance liquid chromatography. Bile acids and fec","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2025-07-01T03:05:46.424Z","creation":"2025-07-01T03:05:46.424Z"},"accession":"S-EPMC12019969","cross_references":{"pubmed":["40065638"],"doi":["10.1093/jas/skaf075"]}}