{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Franken TP"],"funding":["NIDCD NIH HHS"],"pagination":["109202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12019997"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["458"],"pubmed_abstract":["The superior para-olivary nucleus (SPN or SPON) is a prominent nucleus in the superior olivary complex of the auditory brainstem. The cellular composition of the nucleus reportedly differs between species, but a prominent recurring feature is the unusual characteristic to not respond during a sound but at its offset. Blocking glycine has shown that sound-induced inhibition is the mechanism, but the time course of the responsible synaptic events has not been directly measured in vivo. We obtained intracellular recordings in the Mongolian gerbil (meriones unguiculatus) with patch electrodes containing biocytin, and retrieved 12 labeled neurons with large dendritic trees within and around the SPN region. We found that these neurons could be categorized into three classes that show consistency"],"journal":["Hearing research"],"pubmed_title":["Distinct cell classes in the superior paraolivary nucleus (SPN) region in the gerbil auditory brainstem revealed by in vivo physiological and anatomical characterization."],"pmcid":["PMC12019997"],"funding_grant_id":["R01 DC006212"],"pubmed_authors":["Franken TP","Smith PH","Joris PX"],"additional_accession":[]},"is_claimable":false,"name":"Distinct cell classes in the superior paraolivary nucleus (SPN) region in the gerbil auditory brainstem revealed by in vivo physiological and anatomical characterization.","description":"The superior para-olivary nucleus (SPN or SPON) is a prominent nucleus in the superior olivary complex of the auditory brainstem. The cellular composition of the nucleus reportedly differs between species, but a prominent recurring feature is the unusual characteristic to not respond during a sound but at its offset. Blocking glycine has shown that sound-induced inhibition is the mechanism, but the time course of the responsible synaptic events has not been directly measured in vivo. We obtained intracellular recordings in the Mongolian gerbil (meriones unguiculatus) with patch electrodes containing biocytin, and retrieved 12 labeled neurons with large dendritic trees within and around the SPN region. We found that these neurons could be categorized into three classes that show consistency","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2025-07-06T03:04:36.259Z","creation":"2025-07-06T03:04:36.259Z"},"accession":"S-EPMC12019997","cross_references":{"pubmed":["39914279"],"doi":["10.1016/j.heares.2025.109202"]}}