{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Goodburn R"],"funding":["Cancer Research UK"],"pagination":["28-40"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12021324"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["94(1)"],"pubmed_abstract":["Purpose
To measure the gradient system transfer function (GSTF) of an MR-Linac (Elekta Unity, Stockholm, Sweden) using an accessible phantom-based method and to apply trajectory corrections for UTE image reconstruction in the context of MR-guided radiotherapy of lung cancer.Methods
The first-order GSTF of a 1.5 T, split gradient Elekta Unity MR-Linac was measured using a thin-slice technique to characterize gradient system imperfections for each physical gradient axis (X, Y, Z). Repeatability measurements of the GSTF were performed 48 h apart. The GSTF was applied to trajectory correction in multi-echo UTE image reconstruction (TEs = 0.176, 1.85, 3.52 ms) to allow for UTE-Dixon inputs in the generation of synthetic CT. Images were acquired in an anthropomorphic phantom and "],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Gradient system characterization of a 1.5 T MR-Linac with application to 4D UTE imaging for adaptive MR-guided radiotherapy of lung cancer."],"pmcid":["PMC12021324"],"funding_grant_id":["A26234","C33589/A28284"],"pubmed_authors":["Barnes H","Oelfke U","Goodburn R","Bruijnen T","Wetscherek A","Nair P","Ahmed M","Lecoeur B"],"additional_accession":[]},"is_claimable":false,"name":"Gradient system characterization of a 1.5 T MR-Linac with application to 4D UTE imaging for adaptive MR-guided radiotherapy of lung cancer.","description":"Purpose
To measure the gradient system transfer function (GSTF) of an MR-Linac (Elekta Unity, Stockholm, Sweden) using an accessible phantom-based method and to apply trajectory corrections for UTE image reconstruction in the context of MR-guided radiotherapy of lung cancer.Methods
The first-order GSTF of a 1.5 T, split gradient Elekta Unity MR-Linac was measured using a thin-slice technique to characterize gradient system imperfections for each physical gradient axis (X, Y, Z). Repeatability measurements of the GSTF were performed 48 h apart. The GSTF was applied to trajectory correction in multi-echo UTE image reconstruction (TEs = 0.176, 1.85, 3.52 ms) to allow for UTE-Dixon inputs in the generation of synthetic CT. Images were acquired in an anthropomorphic phantom and ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2025-07-01T03:05:32.485Z","creation":"2025-07-01T03:05:32.485Z"},"accession":"S-EPMC12021324","cross_references":{"pubmed":["40106794"],"doi":["10.1002/mrm.30505"]}}