{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li K"],"funding":["NIAID NIH HHS","National Institutes of Health","NIH HHS"],"pagination":["e70111"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12022500"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(4)"],"pubmed_abstract":["<h4>Background</h4>Disruptions in respiratory syncytial virus (RSV) activity were observed in different countries following the 2009 influenza pandemic. Given the limited use of non-pharmaceutical interventions, these disruptions provide an opportunity to probe viral interference due to the out-of-season epidemics. The objectives of the study are twofold: to characterize atypical RSV activity in the United States (US) and to explore the mechanisms underlying changes in RSV epidemics following the pandemic.<h4>Methods</h4>Laboratory-confirmed RSV cases across 10 US regions from June 2007 to July 2019 were analyzed. A dynamic time warping method was used to characterize RSV activity in different seasons. A two-pathogen model was constructed to explore viral interference mechanisms. A samplin"],"journal":["Influenza and other respiratory viruses"],"pubmed_title":["The Role of Viral Interference in Shaping RSV Epidemics Following the 2009 H1N1 Influenza Pandemic."],"pmcid":["PMC12022500"],"funding_grant_id":["R01 AI137093","R01AI137093"],"pubmed_authors":["Pitzer VE","Thindwa D","Li K","Weinberger DM"],"additional_accession":[]},"is_claimable":false,"name":"The Role of Viral Interference in Shaping RSV Epidemics Following the 2009 H1N1 Influenza Pandemic.","description":"<h4>Background</h4>Disruptions in respiratory syncytial virus (RSV) activity were observed in different countries following the 2009 influenza pandemic. Given the limited use of non-pharmaceutical interventions, these disruptions provide an opportunity to probe viral interference due to the out-of-season epidemics. The objectives of the study are twofold: to characterize atypical RSV activity in the United States (US) and to explore the mechanisms underlying changes in RSV epidemics following the pandemic.<h4>Methods</h4>Laboratory-confirmed RSV cases across 10 US regions from June 2007 to July 2019 were analyzed. A dynamic time warping method was used to characterize RSV activity in different seasons. A two-pathogen model was constructed to explore viral interference mechanisms. A samplin","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-09T03:04:56.828Z","creation":"2025-07-09T03:04:56.828Z"},"accession":"S-EPMC12022500","cross_references":{"pubmed":["40275825"],"doi":["10.1111/irv.70111"]}}