{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ioakeim-Skoufa I"],"funding":["Carlos III Institute of Health"],"pagination":["2615"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12028097"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(8)"],"pubmed_abstract":["<b>Background:</b> Managing multimorbidity is a major challenge for healthcare systems. Cardiometabolic multimorbidity (CMM) is highly prevalent and linked to increased disease burden, functional decline, and mortality. While most studies focus on cross-sectional analyses, longitudinal approaches are essential for understanding disease progression and identifying patient groups who may benefit from targeted interventions. <b>Objectives:</b> This systematic review synthesises evidence from longitudinal studies on the incidence and progression of CMM, exploring transitions between multimorbidity clusters and their clinical implications. <b>Methods:</b> A systematic search was conducted in MEDLINE and EMBASE following PRISMA guidelines. Studies were included if they employed longitudinal desi"],"journal":["Journal of clinical medicine"],"pubmed_title":["Charting the Pathways of Cardiometabolic Multimorbidity: A Systematic Review of Clinical Trajectories."],"pmcid":["PMC12028097"],"funding_grant_id":["RD21/0016/0019"],"pubmed_authors":["Hernandez-Rodriguez MA","Aza-Pascual-Salcedo M","Avedillo-Salas A","Gimeno-Miguel A","Ledesma-Calvo R","Ioakeim-Skoufa I","Moreno-Juste A","Cebollada-Herrera C","Atkins K","Lasala-Aza C","Gonzalez-Rubio F","Esteban-Jimenez O","Vicente-Romero J","Roque F"],"additional_accession":[]},"is_claimable":false,"name":"Charting the Pathways of Cardiometabolic Multimorbidity: A Systematic Review of Clinical Trajectories.","description":"<b>Background:</b> Managing multimorbidity is a major challenge for healthcare systems. Cardiometabolic multimorbidity (CMM) is highly prevalent and linked to increased disease burden, functional decline, and mortality. While most studies focus on cross-sectional analyses, longitudinal approaches are essential for understanding disease progression and identifying patient groups who may benefit from targeted interventions. <b>Objectives:</b> This systematic review synthesises evidence from longitudinal studies on the incidence and progression of CMM, exploring transitions between multimorbidity clusters and their clinical implications. <b>Methods:</b> A systematic search was conducted in MEDLINE and EMBASE following PRISMA guidelines. Studies were included if they employed longitudinal desi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-03T03:04:45.535Z","creation":"2025-07-03T03:04:45.535Z"},"accession":"S-EPMC12028097","cross_references":{"pubmed":["40283445"],"doi":["10.3390/jcm14082615"]}}