{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Marecos S"],"funding":["DOE | Advanced Research Projects Agency - Energy (Advanced Research Projects Agency - Energy - U.S. Department of Energy)","National Science Foundation (NSF)","DOE | Advanced Research Projects Agency - Energy","National Science Foundation"],"pagination":["682"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12041372"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(1)"],"pubmed_abstract":["The transition to a sustainable energy economy will require an enormous increase in the supply of rare earth elements (REEs). Bioleaching offers a promising alternative to conventional hydrometallurgical methods for REE extraction from low-grade ores. However, exploiting this potential remains challenging due to large gaps in our understanding of the genetics involved, and inadequate biological tools to address them. We generated a highly non-redundant whole-genome knockout collection for the bioleaching microbe Gluconobacter oxydans B58, reducing redundancy by 85% compared to the previous best collection. This new collection was directly screened for bioleaching neodymium from a synthetic monazite powder, identifying 89 genes important for bioleaching, 68 of which have not previously been"],"journal":["Communications biology"],"pubmed_title":["Direct genome-scale screening of Gluconobacter oxydans B58 for rare earth element bioleaching."],"pmcid":["PMC12041372"],"funding_grant_id":["2435259","DE-AR0001341"],"pubmed_authors":["Pian B","Schmitz A","Wu M","Medin SA","Holycross M","Reid MC","Andrade M","Balta JB","Gazel E","Marecos S","Barstow B"],"additional_accession":[]},"is_claimable":false,"name":"Direct genome-scale screening of Gluconobacter oxydans B58 for rare earth element bioleaching.","description":"The transition to a sustainable energy economy will require an enormous increase in the supply of rare earth elements (REEs). Bioleaching offers a promising alternative to conventional hydrometallurgical methods for REE extraction from low-grade ores. However, exploiting this potential remains challenging due to large gaps in our understanding of the genetics involved, and inadequate biological tools to address them. We generated a highly non-redundant whole-genome knockout collection for the bioleaching microbe Gluconobacter oxydans B58, reducing redundancy by 85% compared to the previous best collection. This new collection was directly screened for bioleaching neodymium from a synthetic monazite powder, identifying 89 genes important for bioleaching, 68 of which have not previously been","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-07-08T03:10:48.339Z","creation":"2025-07-08T03:10:48.339Z"},"accession":"S-EPMC12041372","cross_references":{"pubmed":["40301604"],"doi":["10.1038/s42003-025-08061-4"]}}