{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hawley RS"],"funding":["Swiss National Science Foundation","Stowers Institute for Medical Research","National Institute of Health","American Cancer Society Research","NIH HHS","National Science Foundation"],"pagination":["iyaf039"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12059641"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["230(1)"],"pubmed_abstract":["We present an SNP-based crossover map for Drosophila mauritiana. Using females derived by crossing 2 different strains of D. mauritiana, we analyzed crossing over on all 5 major chromosome arms. Analysis of 105 male progeny allowed us to identify 327 crossover chromatids bearing single, double, or triple crossover events, representing 398 crossover events. We mapped the crossovers along these 5 chromosome arms using a genome sequence map that includes the euchromatin-heterochromatin boundary. Confirming previous studies, we show that the overall crossover frequency in D. mauritiana is higher than is seen in Drosophila melanogaster. Much of the increase in exchange frequency in D. mauritiana is due to a greatly diminished centromere effect. Using larval neuroblast metaphases from D. mauriti"],"journal":["Genetics"],"pubmed_title":["Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over."],"pmcid":["PMC12059641"],"funding_grant_id":["189131","DP5OD033357","2025197","310030_189131","310030","DP5 OD033357"],"pubmed_authors":["Hughes SE","Li H","Lawlor A","Hawley RS","Jagannathan M","Perera A","Miller DE","Price A","Egidy RR","Blumenstiel JP","Staber C","Williams S"],"additional_accession":[]},"is_claimable":false,"name":"Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over.","description":"We present an SNP-based crossover map for Drosophila mauritiana. Using females derived by crossing 2 different strains of D. mauritiana, we analyzed crossing over on all 5 major chromosome arms. Analysis of 105 male progeny allowed us to identify 327 crossover chromatids bearing single, double, or triple crossover events, representing 398 crossover events. We mapped the crossovers along these 5 chromosome arms using a genome sequence map that includes the euchromatin-heterochromatin boundary. Confirming previous studies, we show that the overall crossover frequency in D. mauritiana is higher than is seen in Drosophila melanogaster. Much of the increase in exchange frequency in D. mauritiana is due to a greatly diminished centromere effect. Using larval neuroblast metaphases from D. mauriti","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 May","modification":"2026-04-08T15:43:53.288Z","creation":"2026-04-08T05:20:53.225Z"},"accession":"S-EPMC12059641","cross_references":{"pubmed":["40052765"],"doi":["10.1093/genetics/iyaf039"]}}