biostudies-literatureUnknown22(1)Henriksen HBUniversity of Oslo<h4>Background</h4>Randomized controlled studies (RCTs) targeting dietary changes may also lead to other, untargeted changes in lifestyle habits, as spillover effects. In particular, the isolated impact of the dietary intervention may be difficult to separate due to spillover effects from changes in physical activity and physical function. Therefore, the aim of this study was to investigate the spillover effect of a one-year dietary intervention in post-surgery colorectal cancer patients by comparing the changes in physical activity and physical function between the diet intervention group and the control group in a randomized controlled trial, called the CRC-NORDIET study.<h4>Methods</h4>Men and women, aged 50-80 years were randomized into either the intervention group (n = 240) or the coThe international journal of behavioral nutrition and physical activity54https://www.ebi.ac.uk/biostudies/studies/S-EPMC12063259biostudies-literatureSpillover effect of a dietary intervention on physical activity in a randomized controlled trial with colorectal cancer patients.PMC12063259Berntsen SKolle ABohn SKPaur IBlomhoff RBroto PStenling ATronstad TSHenriksen HBfalseSpillover effect of a dietary intervention on physical activity in a randomized controlled trial with colorectal cancer patients.<h4>Background</h4>Randomized controlled studies (RCTs) targeting dietary changes may also lead to other, untargeted changes in lifestyle habits, as spillover effects. In particular, the isolated impact of the dietary intervention may be difficult to separate due to spillover effects from changes in physical activity and physical function. Therefore, the aim of this study was to investigate the spillover effect of a one-year dietary intervention in post-surgery colorectal cancer patients by comparing the changes in physical activity and physical function between the diet intervention group and the control group in a randomized controlled trial, called the CRC-NORDIET study.<h4>Methods</h4>Men and women, aged 50-80 years were randomized into either the intervention group (n = 240) or the co2025-01-01T00:00:00Z2025 May2026-06-01T14:50:11.885Z2026-04-08T13:27:56.366ZS-EPMC120632594034663910.1186/s12966-025-01757-0