{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["47(2)"],"submitter":["Joo SK"],"pubmed_abstract":["Understanding the effects of sex and sex differences on liver health and disease is crucial for individualized healthcare and informed decision-making for patients with liver disease. The impact of sex on liver disease varies according to its etiology. Women have a lower prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) than men. However, postmenopausal women face a higher risk of advanced liver fibrosis due to hormonal influences. Sex differences affect the pathogenesis of MASLD, which involves a complex process involving several factors such as hormones, obesity, and the gut microbiome. Furthermore, sex-related differences in the development of MASLDrelated hepatocellular carcinoma have been observed. The sex-specific characteristics of MASLD necessitate an i"],"journal":["Ewha medical journal"],"pagination":["e17"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12093579"],"repository":["biostudies-literature"],"pubmed_title":["Sex differences in metabolic dysfunction-associated steatotic liver disease: a narrative review."],"pmcid":["PMC12093579"],"pubmed_authors":["Kim W","Joo SK"],"additional_accession":[]},"is_claimable":false,"name":"Sex differences in metabolic dysfunction-associated steatotic liver disease: a narrative review.","description":"Understanding the effects of sex and sex differences on liver health and disease is crucial for individualized healthcare and informed decision-making for patients with liver disease. The impact of sex on liver disease varies according to its etiology. Women have a lower prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) than men. However, postmenopausal women face a higher risk of advanced liver fibrosis due to hormonal influences. Sex differences affect the pathogenesis of MASLD, which involves a complex process involving several factors such as hormones, obesity, and the gut microbiome. Furthermore, sex-related differences in the development of MASLDrelated hepatocellular carcinoma have been observed. The sex-specific characteristics of MASLD necessitate an i","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Apr","modification":"2026-03-16T04:09:02.515Z","creation":"2025-08-14T03:05:57.691Z"},"accession":"S-EPMC12093579","cross_references":{"pubmed":["40703684"],"doi":["10.12771/emj.2024.e17"]}}