biostudies-literatureUnknownSiegler JENINR NIH HHSNINDS NIH HHSBackgroundEndovascular therapy (EVT) for stroke due to distal or medium vessel occlusion (DMVO) is safe. Due to the distinct anatomical characteristics of DMVOs, further evaluation of EVT is crucial to determine which devices may yield better outcomes.MethodsA retrospective analysis of adults with DMVO treated in 37 centers (11 countries) was queried. The primary outcome of favorable shift in 90-day modified Rankin Scale (mRS) was compared between patients treated with Trevo versus other devices on first pass using 1:1 propensity score matching (PSM) with multivariable adjustment. Secondary outcomes included the number of pass attempts, final thrombolysis in cerebral infarction (TICI) score 2b-3, symptomatic intracranial hemorrhage (sICH), improvement in National Institutes of Health StrokInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences15910199251341603https://www.ebi.ac.uk/biostudies/studies/S-EPMC12095220biostudies-literatureA multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion.PMC12095220R61 NS135583R25 NS065743UE5 NS065743U24 NS113844R21 NR020231R21 NS131756Pedicelli AGriessenauer CJHarker PCostalat VFilipe JPMohlenbruch MAScarcia LDaraghma MVarela RBaker ARegenhardt RWBarreau XRana ALiebeskind DSYedavalli VEssibayi MASheth SAMAD MT InvestigatorsVigilante NMowla ASpears JPuri ASFaizy TDPereira VMShaikh HKhalife JBiswas AKoneru MHenninger NAltschul DTan BYStracke CPGuenego AGonzalez NRTancredi IKuhn ALOta TKalsoum EDyzmann CBernstock JDGory BDmytriw AALubicz BColasurdo MAbdalkader MHeit JJJabbour PSiegler JERadu RAAdeeb NCancelliere NMClarencon FPatel ABRenieri LNguyen TNKlein PGhozy SMusmar BSundararajan SHMarotta TRKass-Hout TNaamani KESalim HAHecker CMorsi RZFiehler JAlexandre AMRouchaud AfalseA multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion.BackgroundEndovascular therapy (EVT) for stroke due to distal or medium vessel occlusion (DMVO) is safe. Due to the distinct anatomical characteristics of DMVOs, further evaluation of EVT is crucial to determine which devices may yield better outcomes.MethodsA retrospective analysis of adults with DMVO treated in 37 centers (11 countries) was queried. The primary outcome of favorable shift in 90-day modified Rankin Scale (mRS) was compared between patients treated with Trevo versus other devices on first pass using 1:1 propensity score matching (PSM) with multivariable adjustment. Secondary outcomes included the number of pass attempts, final thrombolysis in cerebral infarction (TICI) score 2b-3, symptomatic intracranial hemorrhage (sICH), improvement in National Institutes of Health Strok2025-01-01T00:00:00Z2025 May2026-06-02T20:59:16.898Z2026-04-20T03:14:30.183ZS-EPMC120952204039847010.1177/15910199251341603