biostudies-literatureUnknownDi Salle GBackgroundCoil embolization is a standard therapeutic approach for intracranial aneurysms. Recurrence risk during follow-up is not negligible, with inadequate packing density identified as a potential risk factor. This study aims to identify patient- and procedure-related factors contributing to recurrence.MethodsWe retrospectively enrolled consecutive patients with unruptured intracranial aneurysms treated only with coils between January 2021 and December 2022. Aneurysms were included if 3D-rotational angiography and follow-up imaging were available. For each patient, the volume embolization ratio (VER) was computed using Sim&Size^® (Sim&Cure, France) for both the framing coil (First-coil VER) and the entire coiling procedure (Global VER). Patient demographics and aneurysm charaInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences15910199251341652https://www.ebi.ac.uk/biostudies/studies/S-EPMC12095266biostudies-literatureInterdependence of First-coil and Global volume embolization ratios (VERs) calculated by Sim&Size in predicting aneurysm occlusion outcomes.PMC12095266Varnier QGascou GChnafa CCostalat VDi Salle GLefevre PHvan Dokkum LERadu RACollemiche FLCheckouri TAtallah ACagnazzo FRene ADargazanli CfalseInterdependence of First-coil and Global volume embolization ratios (VERs) calculated by Sim&Size in predicting aneurysm occlusion outcomes.BackgroundCoil embolization is a standard therapeutic approach for intracranial aneurysms. Recurrence risk during follow-up is not negligible, with inadequate packing density identified as a potential risk factor. This study aims to identify patient- and procedure-related factors contributing to recurrence.MethodsWe retrospectively enrolled consecutive patients with unruptured intracranial aneurysms treated only with coils between January 2021 and December 2022. Aneurysms were included if 3D-rotational angiography and follow-up imaging were available. For each patient, the volume embolization ratio (VER) was computed using Sim&Size^® (Sim&Cure, France) for both the framing coil (First-coil VER) and the entire coiling procedure (Global VER). Patient demographics and aneurysm chara2025-01-01T00:00:00Z2025 May2026-06-03T02:44:37.283Z2026-04-23T03:10:54.817ZS-EPMC120952664039846910.1177/15910199251341652