biostudies-literatureFichtner UAthe Innovation Fund of Federal Joint Committee – Gemeinsamer Bundesausschuss (G-BA) Germanye0319488https://www.ebi.ac.uk/biostudies/studies/S-EPMC12097750biostudies-literatureUnknown20(4)<h4>Background</h4>Medical screening is employed to detect early signs of diseases in asymptomatic populations, potentially improving patient outcomes through early intervention. However, the psychosocial impact of screenings remains a field of discussion. Inconsistent findings from studies, mainly originally from cancer research, are not easily transferable to the context of liver screening. This study aimed to identify predictors of psychosocial consequences in asymptomatic adults screened for early-stage liver cirrhosis, thereby contributing to the current knowledge on screening impact.<h4>Methods</h4>We analyzed data from 487 participants who underwent a systematic liver disease screening in Germany from January 2018 to February 2021. The screening involved blood tests, advanced diagnoPloS onePredictors for psychosocial consequences of screening for liver diseases: A data-driven approach.PMC1209775001NVF16026Farin-Glattacker EFichtner UAMaun AfalsePredictors for psychosocial consequences of screening for liver diseases: A data-driven approach.<h4>Background</h4>Medical screening is employed to detect early signs of diseases in asymptomatic populations, potentially improving patient outcomes through early intervention. However, the psychosocial impact of screenings remains a field of discussion. Inconsistent findings from studies, mainly originally from cancer research, are not easily transferable to the context of liver screening. This study aimed to identify predictors of psychosocial consequences in asymptomatic adults screened for early-stage liver cirrhosis, thereby contributing to the current knowledge on screening impact.<h4>Methods</h4>We analyzed data from 487 participants who underwent a systematic liver disease screening in Germany from January 2018 to February 2021. The screening involved blood tests, advanced diagno2025-01-01T00:00:00Z20252026-07-15T05:40:05.954Z2026-07-01T03:07:16.87ZS-EPMC120977504029990710.1371/journal.pone.0319488