{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mitchell RAC"],"funding":["Biotechnology and Biological Sciences Research Council"],"pagination":["vbaf079"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12098945"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(1)"],"pubmed_abstract":["<h4>Motivation</h4>Where experiments identify sets of grass genes of unknown function, e.g. underlying a QTL or co-expressed in a transcriptome, it is useful to know which of these genes are common to all grasses (universal) and whether they likely have monocot-/commelinid-/grass-specific function.<h4>Results</h4>A pipeline used data on 16 grass full genomes from Ensembl Plants to generate 13 312 highly conserved, universal groups of grass protein-coding genes. Validation steps showed that 98.8% of these groups also had gene matches in recently sequenced genomes from two major grass clades not used in the pipeline. Comparison with many non-grass genomes identified 4609 of these groups as likely of monocot-/commelinid-/grass-specific function. Both grouping of genes and specificity were def"],"journal":["Bioinformatics advances"],"pubmed_title":["Identification of universal grass genes and estimates of their monocot-/commelinid-/grass-specificity."],"pmcid":["PMC12098945"],"funding_grant_id":["BB/K007599/1"],"pubmed_authors":["Mitchell RAC"],"additional_accession":[]},"is_claimable":false,"name":"Identification of universal grass genes and estimates of their monocot-/commelinid-/grass-specificity.","description":"<h4>Motivation</h4>Where experiments identify sets of grass genes of unknown function, e.g. underlying a QTL or co-expressed in a transcriptome, it is useful to know which of these genes are common to all grasses (universal) and whether they likely have monocot-/commelinid-/grass-specific function.<h4>Results</h4>A pipeline used data on 16 grass full genomes from Ensembl Plants to generate 13 312 highly conserved, universal groups of grass protein-coding genes. Validation steps showed that 98.8% of these groups also had gene matches in recently sequenced genomes from two major grass clades not used in the pipeline. Comparison with many non-grass genomes identified 4609 of these groups as likely of monocot-/commelinid-/grass-specific function. Both grouping of genes and specificity were def","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-04-08T19:09:19.241Z","creation":"2026-04-08T11:58:31.687Z"},"accession":"S-EPMC12098945","cross_references":{"pubmed":["40417655"],"doi":["10.1093/bioadv/vbaf079"]}}