{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yuan HX"],"funding":["National Natural Science Foundation of China","Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of Inner Mongolia Academy of Medical Sciences"],"pagination":["2502003"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12100960"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Wetland virus (WELV) is a recently identified segmented orthonairovirus associated with human febrile illness in northeastern China. To elucidate its ecological drivers and transmission patterns, we conducted multi-host surveillance in seven eco-climate regions across China through an integrated approach combining molecular and serological profiling. Over 33,000 questing and feeding ticks representing 11 species were systematically screened WELV-RNA alongside 1,493 wild small mammals, while 2,578 domestic animals and 3,921 patients presenting with outdoor field or tick exposure history underwent both WELV specific molecular and serological evaluation. WELV-RNA detection via real-time RT-PCR revealed low but widespread infection, including 0.54% (8/1,493) in wild rodents (<i>Apodemus chevri"],"journal":["Emerging microbes & infections"],"pubmed_title":["Genetic diversity and expanded epidemic area of novel tick-borne pathogen wetland virus in ticks, wild and domestic animals, and patient in China."],"pmcid":["PMC12100960"],"funding_grant_id":["82330103","2023GLLH0335"],"pubmed_authors":["Li H","Cui N","Zhao ZJ","Chen M","Zhang XA","Zhang L","Hou ZJ","Zhang MQ","Lv XL","Liu W","Yang X","Han SZ","Si GQ","Peng C","Mu HZ","Yuan HX","Han XH","Bao PT","Ma YD","Wu SQ"],"additional_accession":[]},"is_claimable":false,"name":"Genetic diversity and expanded epidemic area of novel tick-borne pathogen wetland virus in ticks, wild and domestic animals, and patient in China.","description":"Wetland virus (WELV) is a recently identified segmented orthonairovirus associated with human febrile illness in northeastern China. To elucidate its ecological drivers and transmission patterns, we conducted multi-host surveillance in seven eco-climate regions across China through an integrated approach combining molecular and serological profiling. Over 33,000 questing and feeding ticks representing 11 species were systematically screened WELV-RNA alongside 1,493 wild small mammals, while 2,578 domestic animals and 3,921 patients presenting with outdoor field or tick exposure history underwent both WELV specific molecular and serological evaluation. WELV-RNA detection via real-time RT-PCR revealed low but widespread infection, including 0.54% (8/1,493) in wild rodents (<i>Apodemus chevri","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-01T11:37:32.764Z","creation":"2026-04-08T12:00:10.605Z"},"accession":"S-EPMC12100960","cross_references":{"pubmed":["40314229"],"doi":["10.1080/22221751.2025.2502003"]}}