biostudies-literatureGao HNational Natural Science Foundation of China .Central Guidance Fund for Local Science and Technology DevelopmentNatural Science Foundation of NingxiaKey Research and Development projects of Ningxia Hui Autonomous Region4665https://www.ebi.ac.uk/biostudies/studies/S-EPMC12112368biostudies-literatureUnknown26(10)Wolfberry (<i>Lycium barbarum</i> L.) is a valued traditional medicinal plant and dietary supplement in China. The basic leucine zipper (bZIP) transcription factor (TF) family is a multifunctional group of regulatory proteins critical to plant biology, orchestrating processes such as growth and development, secondary metabolite biosynthesis, and stress responses to abiotic conditions. Despite its significance, limited information about this gene family in wolfberry is available. In this study, a total of 66 <i>LbabZIP</i> genes were identified, exhibiting a non-uniform distribution across all 12 chromosomes. Phylogenetic analysis divided these genes into 13 subgroups based on comparison with <i>Arabidopsis</i> bZIP proteins. Analysis of gene structures and conserved motifs revealed high siInternational journal of molecular sciencesGenome-Wide Identification of <i>bZIP</i> Gene Family in <i>Lycium barbarum</i> and Expression During Fruit Development.PMC121123682024FRD05009315604182020AAC032842022BBF02008Yin YCao XZhang XQin XXiong AMa YZheng RGao HBai XfalseGenome-Wide Identification of <i>bZIP</i> Gene Family in <i>Lycium barbarum</i> and Expression During Fruit Development.Wolfberry (<i>Lycium barbarum</i> L.) is a valued traditional medicinal plant and dietary supplement in China. The basic leucine zipper (bZIP) transcription factor (TF) family is a multifunctional group of regulatory proteins critical to plant biology, orchestrating processes such as growth and development, secondary metabolite biosynthesis, and stress responses to abiotic conditions. Despite its significance, limited information about this gene family in wolfberry is available. In this study, a total of 66 <i>LbabZIP</i> genes were identified, exhibiting a non-uniform distribution across all 12 chromosomes. Phylogenetic analysis divided these genes into 13 subgroups based on comparison with <i>Arabidopsis</i> bZIP proteins. Analysis of gene structures and conserved motifs revealed high si2025-01-01T00:00:00Z2025 May2026-04-21T03:22:24.783Z2026-04-21T03:14:29.712ZS-EPMC121123684042980910.3390/ijms26104665