{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Corcione N"],"funding":["Abbott Vascular"],"pagination":["904"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12112984"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(5)"],"pubmed_abstract":["<i>Background and Objectives</i>: Mitral valve transcatheter edge-to-edge repair (TEER) is a widely adopted therapeutic approach for managing significant mitral regurgitation (MR) in high-risk surgical candidates. While procedural safety and efficacy have been demonstrated, the impact of institutional expertise on outcomes remains unclear. We aimed at evaluating whether the institutional monthly volume of TEER influences short- and long-term clinical results. <i>Materials and Methods</i>: This analysis from the multicenter, prospective GIOTTO trial study evaluated the impact of institutional monthly volume on outcomes of TEER to remedy significant mitral regurgitation. Centers were stratified into tertiles based on monthly volumes (≤2.0 cases/month, 2.1-3.5 cases/month, >3.5 cases/month), "],"journal":["Medicina (Kaunas, Lithuania)"],"pubmed_title":["Impact of Institutional Monthly Volume of Transcatheter Edge-to-Edge Repair Procedures for Significant Mitral Regurgitation: Evidence from the GIOTTO-VAT Study."],"pmcid":["PMC12112984"],"funding_grant_id":["NA"],"pubmed_authors":["Giordano A","Morello A","Bartorelli AL","Rubbio AP","Tarantini G","Fiocca L","Giordano S","Giannini F","Castriota F","Denti P","Tamburino C","Ronco F","Ferraro P","Mongiardo A","Bedogni F","Squeri A","Albanese M","Adamo M","Pepe M","De Felice F","Cimmino M","Maisano F","Corcione N","Villa E","Finizio F","Ferrario M","Biondi-Zoccai G","Montorfano M"],"additional_accession":[]},"is_claimable":false,"name":"Impact of Institutional Monthly Volume of Transcatheter Edge-to-Edge Repair Procedures for Significant Mitral Regurgitation: Evidence from the GIOTTO-VAT Study.","description":"<i>Background and Objectives</i>: Mitral valve transcatheter edge-to-edge repair (TEER) is a widely adopted therapeutic approach for managing significant mitral regurgitation (MR) in high-risk surgical candidates. While procedural safety and efficacy have been demonstrated, the impact of institutional expertise on outcomes remains unclear. We aimed at evaluating whether the institutional monthly volume of TEER influences short- and long-term clinical results. <i>Materials and Methods</i>: This analysis from the multicenter, prospective GIOTTO trial study evaluated the impact of institutional monthly volume on outcomes of TEER to remedy significant mitral regurgitation. Centers were stratified into tertiles based on monthly volumes (≤2.0 cases/month, 2.1-3.5 cases/month, >3.5 cases/month), ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 May","modification":"2026-05-28T03:15:15.915Z","creation":"2026-05-28T03:05:47.924Z"},"accession":"S-EPMC12112984","cross_references":{"pubmed":["40428862"],"doi":["10.3390/medicina61050904"]}}