biostudies-literatureUnknown18(6)Ding WT<h4>Aim</h4>To describe an innovative surgical technique for pathologic myopia and macular holes accompanied by retinal detachment using allogeneic corneal stromal lenticule transplantation combined with pars plana vitrectomy.<h4>Methods</h4>The allogeneic corneal stromal lenticule was harvested through small incision lenticule extraction (SMILE) and stored at -30°C in advance. After pars plana vitrectomy, an allogeneic corneal stromal lenticule was thawed, trimmed into approximately 60 µm thick and 100 µm larger than the macular hole and transferred to cover the macular hole through the trocar. Autologous whole blood was dripped to seal the corneal stromal lenticule. The vitreous cavity was then filled with perfluoropropane (C₃F₈) or sterile air.<h4>Results</h4>The tInternational journal of ophthalmology1163-1168https://www.ebi.ac.uk/biostudies/studies/S-EPMC12120465biostudies-literatureCorneal stromal lenticule transplantation for covering macular hole during vitrectomy.PMC12120465Zhang XHLi JQian XXLi DHu YPGe HWHu RJXu YLDing WTfalseCorneal stromal lenticule transplantation for covering macular hole during vitrectomy.<h4>Aim</h4>To describe an innovative surgical technique for pathologic myopia and macular holes accompanied by retinal detachment using allogeneic corneal stromal lenticule transplantation combined with pars plana vitrectomy.<h4>Methods</h4>The allogeneic corneal stromal lenticule was harvested through small incision lenticule extraction (SMILE) and stored at -30°C in advance. After pars plana vitrectomy, an allogeneic corneal stromal lenticule was thawed, trimmed into approximately 60 µm thick and 100 µm larger than the macular hole and transferred to cover the macular hole through the trocar. Autologous whole blood was dripped to seal the corneal stromal lenticule. The vitreous cavity was then filled with perfluoropropane (C₃F₈) or sterile air.<h4>Results</h4>The t2025-01-01T00:00:00Z20252026-04-08T19:23:57.355Z2026-04-08T13:18:17.4ZS-EPMC121204654053479410.18240/ijo.2025.06.24