{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tuttle KR"],"funding":["NIDDK NIH HHS"],"pagination":["101130"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12145773"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["47"],"pubmed_abstract":["<h4>Background</h4>A contemporary description and estimates for rates of chronic kidney disease (CKD) in type 1 diabetes are needed to inform risk reduction strategies. The study aim was to assess prevalence and severity of CKD based on a population with type 1 diabetes receiving care at a large United States health system.<h4>Methods</h4>Type 1 diabetes was identified through the Providence health system electronic health records during 2013-2022. Prevalent CKD was defined cross-sectionally by ≥ 90-day persistence of estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m<sup>2</sup>, urine albumin-to-creatinine ratio ≥30 mg/g, or urine protein-to-creatinine ratio ≥0.15 g/g. Multivariable logistic regression models analyzed variable associations with CKD and severe kidney disease ("],"journal":["Lancet regional health. Americas"],"pubmed_title":["Prevalence and severity of chronic kidney disease in a population with type 1 diabetes from a United States health system: a real-world cohort study."],"pmcid":["PMC12145773"],"funding_grant_id":["P30 DK017047"],"pubmed_authors":["Duru OK","Neumiller JJ","Nicholas SB","Xu F","Norris KC","CURE-CKD Consortium","Tuttle KR","Greenbaum C","Kornowske LM","Pavkov ME","Jones CR","Alicic RZ","Reynolds CL","Daratha KB"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and severity of chronic kidney disease in a population with type 1 diabetes from a United States health system: a real-world cohort study.","description":"<h4>Background</h4>A contemporary description and estimates for rates of chronic kidney disease (CKD) in type 1 diabetes are needed to inform risk reduction strategies. The study aim was to assess prevalence and severity of CKD based on a population with type 1 diabetes receiving care at a large United States health system.<h4>Methods</h4>Type 1 diabetes was identified through the Providence health system electronic health records during 2013-2022. Prevalent CKD was defined cross-sectionally by ≥ 90-day persistence of estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m<sup>2</sup>, urine albumin-to-creatinine ratio ≥30 mg/g, or urine protein-to-creatinine ratio ≥0.15 g/g. Multivariable logistic regression models analyzed variable associations with CKD and severe kidney disease (","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-05-26T20:01:31.138Z","creation":"2026-05-26T03:06:19.097Z"},"accession":"S-EPMC12145773","cross_references":{"pubmed":["40486991"],"doi":["10.1016/j.lana.2025.101130"]}}