{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15"],"submitter":["Botelho J"],"pubmed_abstract":["<h4>Aim</h4>Antimicrobial stewardship envisions the appropriate use of antimicrobials, including antibiotics. Antibiotic therapy in Periodontology has been widely investigated over the years. This umbrella review aimed to appraise the methodological quality and meta-analytical strength and validity of the evidence of systematic reviews (SRs) on systemic and local antibiotics in periodontal therapy.<h4>Material and methods</h4>After registration of the protocol (PROSPERO CRD42024527222), an extensive search, up to March 2024, for SRs that have assessed the effect of antibiotics in periodontal therapy, either nonsurgical and surgical, regardless of the types of patients and type of antibiotic. The methodological quality of SRs was judged using A MeaSurement Tool to Assess systematic Reviews "],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["1601464"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12174147"],"repository":["biostudies-literature"],"pubmed_title":["Antibiotics in periodontal treatment: an umbrella review."],"pmcid":["PMC12174147"],"pubmed_authors":["Lyra P","Nascimento GG","Leite FRM","Mendes JJ","Machado V","Botelho J"],"additional_accession":[]},"is_claimable":false,"name":"Antibiotics in periodontal treatment: an umbrella review.","description":"<h4>Aim</h4>Antimicrobial stewardship envisions the appropriate use of antimicrobials, including antibiotics. Antibiotic therapy in Periodontology has been widely investigated over the years. This umbrella review aimed to appraise the methodological quality and meta-analytical strength and validity of the evidence of systematic reviews (SRs) on systemic and local antibiotics in periodontal therapy.<h4>Material and methods</h4>After registration of the protocol (PROSPERO CRD42024527222), an extensive search, up to March 2024, for SRs that have assessed the effect of antibiotics in periodontal therapy, either nonsurgical and surgical, regardless of the types of patients and type of antibiotic. The methodological quality of SRs was judged using A MeaSurement Tool to Assess systematic Reviews ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-03-31T10:45:10.18Z","creation":"2025-08-28T03:05:51.751Z"},"accession":"S-EPMC12174147","cross_references":{"pubmed":["40535546"],"doi":["10.3389/fcimb.2025.1601464"]}}