{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Smith SL"],"funding":["Versus Arthritis","National Institute for Health Research (NIHR)","Wellcome Trust"],"pagination":["e1295"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12185087"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(4)"],"pubmed_abstract":["<h4>Introduction</h4>The central nervous system (CNS) contributes to pain perception across musculoskeletal conditions. The central aspects of pain (CAP) questionnaire captures a single score associated with quantitative sensory testing (QST) evidence of CNS dysfunction validated in knee osteoarthritis.<h4>Objectives</h4>Given the different pathophysiology of rheumatoid arthritis (RA), an inflammatory polyarthritis, this cross-sectional study assessed CAP's psychometric properties and its association with pain in RA.<h4>Methods</h4>Adults with RA were recruited from Nottinghamshire, London, and Cardiff. Participants completed CAP and reported pain using a numerical rating scale. A subgroup underwent additional assessments, including quantitative sensory testing (QST; Pressure Pain detectio"],"journal":["Pain reports"],"pubmed_title":["Validity and contributions to pain from the central aspects of pain questionnaire in rheumatoid arthritis."],"pmcid":["PMC12185087"],"funding_grant_id":["224257/Z/21/Z","22462","20777","NIHR301674"],"pubmed_authors":["Ledbury S","McWilliams DF","Platts D","Ifesemen OS","Pickles T","Rutter-Locher Z","Kirkham B","James R","Wilson D","Walsh DA","Georgopoulos V","Choy E","Ferguson E","Wakefield RJ","Buckley P","Smith SL"],"additional_accession":[]},"is_claimable":false,"name":"Validity and contributions to pain from the central aspects of pain questionnaire in rheumatoid arthritis.","description":"<h4>Introduction</h4>The central nervous system (CNS) contributes to pain perception across musculoskeletal conditions. The central aspects of pain (CAP) questionnaire captures a single score associated with quantitative sensory testing (QST) evidence of CNS dysfunction validated in knee osteoarthritis.<h4>Objectives</h4>Given the different pathophysiology of rheumatoid arthritis (RA), an inflammatory polyarthritis, this cross-sectional study assessed CAP's psychometric properties and its association with pain in RA.<h4>Methods</h4>Adults with RA were recruited from Nottinghamshire, London, and Cardiff. Participants completed CAP and reported pain using a numerical rating scale. A subgroup underwent additional assessments, including quantitative sensory testing (QST; Pressure Pain detectio","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-06-03T06:56:46.674Z","creation":"2026-04-25T03:22:11.02Z"},"accession":"S-EPMC12185087","cross_references":{"pubmed":["40551746"],"doi":["10.1097/PR9.0000000000001295"]}}