{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Liu J"],"funding":["NIBIB NIH HHS","NCRR NIH HHS","NINDS NIH HHS"],"pubmed_abstract":["<h4>Purpose</h4>To demonstrate the feasibility and performance of mesoscopic whole brain T<sub>2</sub>*-weighted (T<sub>2</sub>*w) MRI at 10.5 T by combining a motion-robust multi-echo gradient-echo (GRE) method with high-density RF receive arrays.<h4>Methods</h4>Multi-echo GRE data were collected in healthy adults at isotropic 0.5 mm resolution using a custom-built 16-channel transmit/80-channel receive (16Tx/80Rx) RF coil. Whole brain images were reconstructed with navigator-guided joint motion and field correction and were used for quantitative <i>R</i> <sub>2</sub>* and susceptibility (<i>χ</i>) mapping. Intrinsic signal-to-noise ratio (iSNR) and quantification precision for <i>R</i> <sub>2</sub>* and <i>χ</i> were also estimated. The results were compared with those obtained in the sa"],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2025.04.21.649819"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12190817"],"repository":["biostudies-literature"],"pubmed_title":["Mesoscopic whole-brain T&lt;sub&gt;2&lt;/sub&gt;*-weighted and associated quantitative MRI in healthy humans at 10.5 T."],"pmcid":["PMC12190817"],"funding_grant_id":["R01 NS136490","P41 EB027061","S10 RR029672","U01 EB025144"],"pubmed_authors":["Waks M","Liu J","Auerbach E","Eryaman Y","Lagore R","Ugurbil K","Adriany G","Grant A","Duyn JH","Delabarre L","Huang Y","Sadeghi-Tarakameh A","van Gelderen P","de Zwart JA","Wu X"],"additional_accession":[]},"is_claimable":false,"name":"Mesoscopic whole-brain T&lt;sub&gt;2&lt;/sub&gt;*-weighted and associated quantitative MRI in healthy humans at 10.5 T.","description":"<h4>Purpose</h4>To demonstrate the feasibility and performance of mesoscopic whole brain T<sub>2</sub>*-weighted (T<sub>2</sub>*w) MRI at 10.5 T by combining a motion-robust multi-echo gradient-echo (GRE) method with high-density RF receive arrays.<h4>Methods</h4>Multi-echo GRE data were collected in healthy adults at isotropic 0.5 mm resolution using a custom-built 16-channel transmit/80-channel receive (16Tx/80Rx) RF coil. Whole brain images were reconstructed with navigator-guided joint motion and field correction and were used for quantitative <i>R</i> <sub>2</sub>* and susceptibility (<i>χ</i>) mapping. Intrinsic signal-to-noise ratio (iSNR) and quantification precision for <i>R</i> <sub>2</sub>* and <i>χ</i> were also estimated. The results were compared with those obtained in the sa","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2026-04-08T16:12:25.21Z","creation":"2026-04-08T06:11:04.806Z"},"accession":"S-EPMC12190817","cross_references":{"pubmed":["40568064"],"doi":["10.1101/2025.04.21.649819"]}}