{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Qin Q"],"funding":["supported by Pests and Diseases Green Prevention and Control Major Special Project"],"pagination":["446"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12194751"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(6)"],"pubmed_abstract":["The fungus <i>Alternaria alternata</i>, which causes tobacco brown spot disease, poses a serious threat to the tobacco industry. Beneficial microorganisms and their secondary metabolites have emerged as a promising green strategy for disease management. This study recovered 16 endophytic bacterial strains from <i>Mentha haplocalyx</i> Briq., a therapeutic herb. The study revealed that strain B5, with an inhibition rate of 82.76%, exhibited the highest antifungal activity against <i>A. alternata</i>. This strain exhibited broad-spectrum antifungal activity, with inhibition rates ranging from 66.34% to 87.23%. Phylogenetic analysis of 16S rDNA and <i>gyrA</i> gene sequences identified it as <i>Bacillus velezensis</i> (GenBank: PV168970 and PV173738). Further characterization revealed that st"],"journal":["Journal of fungi (Basel, Switzerland)"],"pubmed_title":["Isolation and Identification of Endophytic Bacterium B5 from &lt;i&gt;Mentha haplocalyx&lt;/i&gt; Briq. and Its Biocontrol Mechanisms Against &lt;i&gt;Alternaria alternata&lt;/i&gt;-Induced Tobacco Brown Spot."],"pmcid":["PMC12194751"],"funding_grant_id":["110202201023 ( LS-07 )"],"pubmed_authors":["Qin Q","Ma B","Liu B","Wei X","Zhou Y","Sun Z"],"additional_accession":[]},"is_claimable":false,"name":"Isolation and Identification of Endophytic Bacterium B5 from &lt;i&gt;Mentha haplocalyx&lt;/i&gt; Briq. and Its Biocontrol Mechanisms Against &lt;i&gt;Alternaria alternata&lt;/i&gt;-Induced Tobacco Brown Spot.","description":"The fungus <i>Alternaria alternata</i>, which causes tobacco brown spot disease, poses a serious threat to the tobacco industry. Beneficial microorganisms and their secondary metabolites have emerged as a promising green strategy for disease management. This study recovered 16 endophytic bacterial strains from <i>Mentha haplocalyx</i> Briq., a therapeutic herb. The study revealed that strain B5, with an inhibition rate of 82.76%, exhibited the highest antifungal activity against <i>A. alternata</i>. This strain exhibited broad-spectrum antifungal activity, with inhibition rates ranging from 66.34% to 87.23%. Phylogenetic analysis of 16S rDNA and <i>gyrA</i> gene sequences identified it as <i>Bacillus velezensis</i> (GenBank: PV168970 and PV173738). Further characterization revealed that st","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jun","modification":"2026-04-08T19:37:41.01Z","creation":"2026-04-08T13:56:07.484Z"},"accession":"S-EPMC12194751","cross_references":{"pubmed":["40558958"],"doi":["10.3390/jof11060446"]}}