biostudies-literatureRossi LPaolo GaibaniCaterina Signorettomyaf054https://www.ebi.ac.uk/biostudies/studies/S-EPMC12203899biostudies-literatureUnknown63(6)We characterized the genome of the clinical Trichophyton mentagrophytes genotype VII strain PG12DES. PG12DES genome harbored different virulence factors, including MEP-1, MEP-2, MEP-3, MEP-4, SUB-6, and ZAF-A. Phylogenetic analysis revealed that PG12DES was clonally related to a T. mentagrophytes strain isolated in Moldova in 2017. This study provides the genome characterization of a clinical strain from Italy and broadens the knowledge of the emergent genotype VII.Medical mycologyGenome characterization of Trichophyton mentagrophytes genotype VII strain PG12DES from Italy.PMC12203899FUR2024Signoretto PCGaibani PRossi LSorrentino AfalseGenome characterization of Trichophyton mentagrophytes genotype VII strain PG12DES from Italy.We characterized the genome of the clinical Trichophyton mentagrophytes genotype VII strain PG12DES. PG12DES genome harbored different virulence factors, including MEP-1, MEP-2, MEP-3, MEP-4, SUB-6, and ZAF-A. Phylogenetic analysis revealed that PG12DES was clonally related to a T. mentagrophytes strain isolated in Moldova in 2017. This study provides the genome characterization of a clinical strain from Italy and broadens the knowledge of the emergent genotype VII.2025-01-01T00:00:00Z2025 Jun2026-06-01T15:36:30.91Z2026-04-08T13:38:36.677ZS-EPMC122038994057704310.1093/mmy/myaf054