biostudies-literatureJordan-Lopez JMinisterio de Ciencia e Innovación20372https://www.ebi.ac.uk/biostudies/studies/S-EPMC12214722biostudies-literatureUnknown15(1)Movement-evoked pain in chronic low back pain (LBP) can be influenced by visual cues linked to threatening movements. This study explored whether manipulating visual proprioceptive feedback via virtual reality (VR) alters movement-evoked pain and if individuals with higher pain, kinesiophobia, disability, or catastrophising are more susceptible to these manipulations. Cross-sectional study with 50 patients with non-specific chronic LBP. Participants performed lumbar spine extension until pain onset with and without VR. VR feedback was manipulated to show 10% less (E -) or 10% more (E +) movement than actual extension. Range of motion (ROM) was measured using an electro-goniometer. Within-group differences across control (E), E -, and E + conditions were assessed with Friedman tests. VR undScientific reportsVisual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain.PMC12214722PID2020-115609RB-C22Lison JFMiragall MJordan-Lopez JBanos RMArguisuelas MDPenalver-Barrios MLHerrero RAmer-Cuenca JJDomenech JfalseVisual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain.Movement-evoked pain in chronic low back pain (LBP) can be influenced by visual cues linked to threatening movements. This study explored whether manipulating visual proprioceptive feedback via virtual reality (VR) alters movement-evoked pain and if individuals with higher pain, kinesiophobia, disability, or catastrophising are more susceptible to these manipulations. Cross-sectional study with 50 patients with non-specific chronic LBP. Participants performed lumbar spine extension until pain onset with and without VR. VR feedback was manipulated to show 10% less (E -) or 10% more (E +) movement than actual extension. Range of motion (ROM) was measured using an electro-goniometer. Within-group differences across control (E), E -, and E + conditions were assessed with Friedman tests. VR und2025-01-01T00:00:00Z2025 Jul2026-06-01T16:03:23.739Z2026-04-08T13:59:43.959ZS-EPMC122147224059653010.1038/s41598-025-08094-z