biostudies-literatureUnknown77(3)Bhuvaneswaran Kartha GA hemodynamically significant patent ductus arteriosus (PDA) may be associated with mitral regurgitation (MR). Available treatment strategies are - surgical PDA ligation ± mitral valve surgery and initial transcatheter PDA closure (PDA-DC) with treatment of MR subsequently, if necessary. We aimed to describe the fate of MR after PDA-DC in patients with PDA and significant MR. On retrospective review of electronic health records between 2013 and 2023, 14 eligible patients were identified. Amongst them, PDA-DC resulted in symptomatic improvement in all. A reduction in the severity of MR was noted in 12 patients (85.7 %).Indian heart journal231-234https://www.ebi.ac.uk/biostudies/studies/S-EPMC12223595biostudies-literatureFate of mitral regurgitation after transcatheter closure of patent ductus arteriosus: single centre study.PMC12223595Bhuvaneswaran Kartha GIrene Varghese SKrupa JSamuel Thomson VGeorge OKGeorge Alex AfalseFate of mitral regurgitation after transcatheter closure of patent ductus arteriosus: single centre study.A hemodynamically significant patent ductus arteriosus (PDA) may be associated with mitral regurgitation (MR). Available treatment strategies are - surgical PDA ligation ± mitral valve surgery and initial transcatheter PDA closure (PDA-DC) with treatment of MR subsequently, if necessary. We aimed to describe the fate of MR after PDA-DC in patients with PDA and significant MR. On retrospective review of electronic health records between 2013 and 2023, 14 eligible patients were identified. Amongst them, PDA-DC resulted in symptomatic improvement in all. A reduction in the severity of MR was noted in 12 patients (85.7 %).2025-01-01T00:00:00Z2025 May-Jun2026-06-15T06:09:21.749Z2026-06-15T03:08:37.065ZS-EPMC122235954018909710.1016/j.ihj.2025.04.001