{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["68(1)"],"submitter":["Ma H"],"pubmed_abstract":["<h4>Background</h4>Rotavirus (RV) A is one of the major reasons which causes acute dehydration and diarrhea. It is also one of the highest morbid diseases in children. There are only a few reports about the changes in prevalence and VP4/VP7 genotype of RVs in southwest China. Here is the report about the prevalence of RVs from 2015 to 2020 in Yunnan, southwest China.<h4>Methods</h4>The virus genes were extracted from RV positive samples, then VP4/VP7 genes were amplified, followed by sequencing and gene typing, phylogenetic analysis, antigenic epitope variation analysis, and selective pressure analysis were also performed.<h4>Results</h4>A total of 135 VP4 gene sequences and 143 VP7 gene sequences were obtained from stool samples during 2015-2020. Of them, P[8] genotype accounted for 97.0%"],"journal":["Intervirology"],"pagination":["43-56"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12237282"],"repository":["biostudies-literature"],"pubmed_title":["Genetic and Antigenic Variability in VP4 and VP7 of Group A Human Rotavirus in Yunnan, China, from 2015 to 2020."],"pmcid":["PMC12237282"],"pubmed_authors":["Wang M","Zhao C","Sun Q","Zhang Z","Jiang H","Ma H","Chuan L","Long S","Qiu L"],"additional_accession":[]},"is_claimable":false,"name":"Genetic and Antigenic Variability in VP4 and VP7 of Group A Human Rotavirus in Yunnan, China, from 2015 to 2020.","description":"<h4>Background</h4>Rotavirus (RV) A is one of the major reasons which causes acute dehydration and diarrhea. It is also one of the highest morbid diseases in children. There are only a few reports about the changes in prevalence and VP4/VP7 genotype of RVs in southwest China. Here is the report about the prevalence of RVs from 2015 to 2020 in Yunnan, southwest China.<h4>Methods</h4>The virus genes were extracted from RV positive samples, then VP4/VP7 genes were amplified, followed by sequencing and gene typing, phylogenetic analysis, antigenic epitope variation analysis, and selective pressure analysis were also performed.<h4>Results</h4>A total of 135 VP4 gene sequences and 143 VP7 gene sequences were obtained from stool samples during 2015-2020. Of them, P[8] genotype accounted for 97.0%","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-07-15T12:44:44.244Z","creation":"2026-07-04T03:16:24.995Z"},"accession":"S-EPMC12237282","cross_references":{"pubmed":["40300562"],"doi":["10.1159/000546065"]}}