{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["42(8)"],"submitter":["Michaels VR"],"funding":["Lions New Zealand District 202F","Otago Southland Diabetes Research Trust","Bowen Family Foundation","Lottery Health Research","Spinal Cord Society of New Zealand","University of Otago Wellington","Lloyd Morgan Lions Clubs Charitable Trust","Starship Foundation"],"pubmed_abstract":["<h4>Aims</h4>To assess how automated insulin delivery (AID) impacts sleep in young people with type 1 diabetes and suboptimal glycaemia (HbA1c ≥ 69 mmol/mol).<h4>Methods</h4>We conducted a randomised controlled trial comparing AID to usual care in 80 participants (aged 7-25 years) over 13 weeks. Sleep was a secondary outcome assessed at baseline and 13 weeks using questionnaires (subjective) and accelerometry (objective).<h4>Results</h4>All participants completed the trial; 64 provided subjective and 40 provided objective sleep data. Participants reported poor subjective sleep quality alongside high levels of sleep disturbance and sleep-related impairment at both timepoints. At 13 weeks, sleep-related impairment improved more in the intervention group than in controls (MD = -4.7; 95% CI = "],"journal":["Diabetic medicine : a journal of the British Diabetic Association"],"pagination":["e70093"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12257429"],"repository":["biostudies-literature"],"pubmed_title":["Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c: Sleep outcomes from the CO-PILOT randomised controlled trial."],"pmcid":["PMC12257429"],"pubmed_authors":["Haszard JJ","Wiltshire E","Jefferies C","Michaels VR","Paul RG","de Bock MI","Boucsein A","Jones SD","Galland B","Zhou Y","Wheeler BJ","Meredith-Jones KA"],"additional_accession":[]},"is_claimable":false,"name":"Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c: Sleep outcomes from the CO-PILOT randomised controlled trial.","description":"<h4>Aims</h4>To assess how automated insulin delivery (AID) impacts sleep in young people with type 1 diabetes and suboptimal glycaemia (HbA1c ≥ 69 mmol/mol).<h4>Methods</h4>We conducted a randomised controlled trial comparing AID to usual care in 80 participants (aged 7-25 years) over 13 weeks. Sleep was a secondary outcome assessed at baseline and 13 weeks using questionnaires (subjective) and accelerometry (objective).<h4>Results</h4>All participants completed the trial; 64 provided subjective and 40 provided objective sleep data. Participants reported poor subjective sleep quality alongside high levels of sleep disturbance and sleep-related impairment at both timepoints. At 13 weeks, sleep-related impairment improved more in the intervention group than in controls (MD = -4.7; 95% CI = ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-06-10T05:19:46.508Z","creation":"2026-06-10T03:07:08.833Z"},"accession":"S-EPMC12257429","cross_references":{"pubmed":["40534171"],"doi":["10.1111/dme.70093"]}}