{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(3)"],"submitter":["Mitra A"],"pubmed_abstract":["Anti-N-methyl-ᴅ-aspartate (anti-NMDA) receptor encephalitis is a well-known autoimmune encephalitis caused by antibodies against the GluN1 subunit of the anti-NMDA receptor (anti-NMDAR). Stroke, characterized by abrupt focal neurological deficits due to ischemic or hemorrhagic vascular insults, is rarely preceded by anti-NMDAR encephalitis. Here, we described a case of a 69-year-old female without any prior comorbidities who presented with acute stroke and left hemiparesis with a history of recent onset of neuropsychiatric symptoms. Her cerebrospinal fluid was positive for anti-NMDAR antibody, and significant improvement was noticed after the initiation of immunotherapy. In this patient, stroke occurred following anti-NMDAR encephalitis; however, the pathophysiological link between the two"],"journal":["Encephalitis (Seoul, Korea)"],"pagination":["71-76"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12268045"],"repository":["biostudies-literature"],"pubmed_title":["Anti-N-methyl-ᴅ-aspartate receptor encephalitis preceding stroke: report of an unusual case with literature review."],"pmcid":["PMC12268045"],"pubmed_authors":["Srivastava NK","Mishra VN","Pathak A","Vivek A","Mitra A"],"additional_accession":[]},"is_claimable":false,"name":"Anti-N-methyl-ᴅ-aspartate receptor encephalitis preceding stroke: report of an unusual case with literature review.","description":"Anti-N-methyl-ᴅ-aspartate (anti-NMDA) receptor encephalitis is a well-known autoimmune encephalitis caused by antibodies against the GluN1 subunit of the anti-NMDA receptor (anti-NMDAR). Stroke, characterized by abrupt focal neurological deficits due to ischemic or hemorrhagic vascular insults, is rarely preceded by anti-NMDAR encephalitis. Here, we described a case of a 69-year-old female without any prior comorbidities who presented with acute stroke and left hemiparesis with a history of recent onset of neuropsychiatric symptoms. Her cerebrospinal fluid was positive for anti-NMDAR antibody, and significant improvement was noticed after the initiation of immunotherapy. In this patient, stroke occurred following anti-NMDAR encephalitis; however, the pathophysiological link between the two","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-03-16T00:20:01.017Z","creation":"2025-08-14T03:05:16.332Z"},"accession":"S-EPMC12268045","cross_references":{"pubmed":["40635309"],"doi":["10.47936/encephalitis.2025.00017"]}}