{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["51"],"submitter":["Wu Y"],"pubmed_abstract":["The expanding global population intensifies demand for sustainable protein sources. Cell-cultured meat (CM) offers a promising alternative to conventional meat production but faces challenges in scalability and food-grade scaffold design. Current scaffolds often fail to replicate muscle tissue's structural and mechanical properties or support large-scale CM production. Moreover, the sensory and nutritional qualities of CM remain understudied. Here, we developed a novel lotus fiber-based natural plant fiber (NPF) scaffold mimicking native muscle tissue architecture. Porcine muscle stem cells (pMuSCs) were cultured on the NPF scaffold (pMuSCs-NPF), and their viability, proliferation, and differentiation were evaluated. The NPF scaffolds exhibited high biocompatibility and promoted pMuSCs ali"],"journal":["Bioactive materials"],"pagination":["807-824"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12268086"],"repository":["biostudies-literature"],"pubmed_title":["Lotus fiber-derived scaffolds for enhanced cultured meat production: Quality and sustainability."],"pmcid":["PMC12268086"],"pubmed_authors":["Tang J","Li Y","He C","Shi L","Yang Q","Zhang C","Dai J","Wu Y"],"additional_accession":[]},"is_claimable":false,"name":"Lotus fiber-derived scaffolds for enhanced cultured meat production: Quality and sustainability.","description":"The expanding global population intensifies demand for sustainable protein sources. Cell-cultured meat (CM) offers a promising alternative to conventional meat production but faces challenges in scalability and food-grade scaffold design. Current scaffolds often fail to replicate muscle tissue's structural and mechanical properties or support large-scale CM production. Moreover, the sensory and nutritional qualities of CM remain understudied. Here, we developed a novel lotus fiber-based natural plant fiber (NPF) scaffold mimicking native muscle tissue architecture. Porcine muscle stem cells (pMuSCs) were cultured on the NPF scaffold (pMuSCs-NPF), and their viability, proliferation, and differentiation were evaluated. The NPF scaffolds exhibited high biocompatibility and promoted pMuSCs ali","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-03-27T15:54:27.535Z","creation":"2025-08-24T03:09:05.927Z"},"accession":"S-EPMC12268086","cross_references":{"pubmed":["40678262"],"doi":["10.1016/j.bioactmat.2025.06.048"]}}